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ORNL’s biosensor system reveals CRISPR activity in poplar plants, which glow bright green under ultraviolet light, compared to normal plants, which appear red. Credit: Guoliang Yuan/ORNL, U.S. Dept. of Energy

Detecting the activity of CRISPR gene editing tools in organisms with the naked eye and an ultraviolet flashlight is now possible using technology developed at ORNL. 

Carrie Eckert

Carrie Eckert applies her skills as a synthetic biologist at ORNL to turn microorganisms into tiny factories that produce a variety of valuable fuels, chemicals and materials for the growing bioeconomy.

ORNL metabolic engineer Adam Guss develops genetic tools to modify microbes that can perform a range of processes needed to create sustainable biofuels and bioproducts. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

As a metabolic engineer at Oak Ridge National Laboratory, Adam Guss modifies microbes to perform the diverse processes needed to make sustainable biofuels and bioproducts.

ORNL’s Josh Michener, a microbiologist and metabolic engineer, led the discovery of a useful new enzyme that breaks down stubborn bonds in lignin, a polymer found in plants that typically becomes waste during bioconversion. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

In a step toward increasing the cost-effectiveness of renewable biofuels and bioproducts, scientists at ORNL discovered a microbial enzyme that degrades tough-to-break bonds in lignin, a waste product of biorefineries.

Scientists genetically engineered bacteria for itaconic acid production, creating dynamic controls that separate microbial growth and production phases for increased efficiency and acid yield. Credit: NREL

A research team led by Oak Ridge National Laboratory bioengineered a microbe to efficiently turn waste into itaconic acid, an industrial chemical used in plastics and paints.