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Biotechnology - Regenerating skin, muscle

Researchers at the Bio-SANS instrument at the High Flux Isotope Reactor used contrast variation and small-angle neutron scattering to get a first insight into how macromolecules form single polyelectrolyte chains in synthetic complexes. The unique properties of polyelectrolyte materials are of intense interest in biotechnology for making a type of membrane „ three-dimensional bio-scaffolds to grow cells for regenerating skin, muscle and even organs. Little is known about how the component chains in polyelectrolyte complexes form themselves, whether as strings or as coils, inside the bulk material. The SANS work will assist researchers in tuning thickness, uniformity, stability, swelling, permeability and other important variables. The results could open the door to multiple future applications. - Agatha Bardoel, 865.574.0644, February 21, 2012