Scientists examining cells to study diseases and potential cures could one day have a new tool that advances the field to a level previously only imagined. The digital holography technique detailed in OPTICS EXPRESS allows for high-precision 3D single-shot real-time recording that set new standards in the field. "This technology will give biologists the third dimension they need to study cells in great detail and it allows them to interact with a cell to see how it reacts to various drugs," said Chris Mann, a Wigner Fellow and member of Oak Ridge National Laboratory's Measurement Science and Systems Engineering Division. Specifically, Mann notes that the level of resolution and detail in images obtained with this new method clearly exceed those available today in phase-contrast optical microscopy. This research is funded by the Laboratory Directed Research and Development program.
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