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ORNL scientists mutated amino acids in a receptor protein, shown in green, which diminished interaction with the SARS-CoV-2 virus spike protein, shown in red. Mutating the receptor protein hampered the virus’s ability to infect host cells. Credit: ORNL, U.S. Dept. of Energy

Oak Ridge National Laboratory scientists exploring bioenergy plant genetics have made a surprising discovery: a protein domain that could lead to new COVID-19 treatments.

Oak Ridge National Laboratory led a team of scientists to design a molecule that disrupts the infection mechanism of the SARS-CoV-2 coronavirus and could be used to develop new treatments for COVID-19 and future virus outbreaks. Credit: Michelle Lehman/ORNL, U.S. Dept. of Energy

A team of scientists led by the Department of Energy’s Oak Ridge National Laboratory designed a molecule that disrupts the infection mechanism of the SARS-CoV-2 coronavirus and could be used to develop new treatments for COVID-19 and other viral diseases.

This newly manufactured fixed guide vane of a hydropower turbine system was printed at the DOE Manufacturing Demonstration Facility at ORNL. Credit: Genevieve Martin/ORNL, U.S Dept. of Energy

A new report published by ORNL assessed how advanced manufacturing and materials, such as 3D printing and novel component coatings, could offer solutions to modernize the existing fleet and design new approaches to hydropower.

Technology to retrofit nonpowered dams such as the Lake Sequoyah Dam in North Carolina could be tested before deploying to ensure performance and reliability. Credit: Scott DeNeale/ORNL, U.S. Dept. of Energy

Researchers at Oak Ridge National Laboratory have identified a key need for future hydropower innovations – full-scale testing – to better inform developers and operators before making major investments.

ORNL’s Adam Guss and colleagues used synthetic biology to develop a custom microbe capable of converting deconstructed mixed plastic waste into valuable new materials. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

Scientists working on a solution for plastic waste have developed a two-step chemical and biological process to break down and upcycle mixed plastics into valuable bioproducts.

Conduit hydropower presents opportunities in every state. Credit: ORNL, U.S. Dept. of Energy

Millions of miles of pipelines and conduits across the United States make up an intricate network of waterways used for municipal, agricultural and industrial purposes.

ORNL is studying how climate change may impact water availability for hydropower facilities such as the Shasta Dam and Lake in California. Credit: U.S. Bureau of Reclamation

ORNL has provided hydropower operators with new data to better prepare for extreme weather events and shifts in seasonal energy demands caused by climate change.

Melton Hill Dam

To further the potential benefits of the nation’s hydropower resources, researchers at Oak Ridge National Laboratory have developed and maintain a comprehensive water energy digital platform called HydroSource.

non-powered dam

Although more than 92,000 dams populate the country, the vast majority — about 89,000 — do not generate electricity through hydropower.

ORNL researchers deploy a gas trap to measure ebullitive (bubbling) emissions of methane at the Melton Dam in East Tennessee. The trap is deployed for ~ 24 hours to allow gas to accumulate in the trap. Credit: Carlos Jones/ORNL, US Dept. of Energy

As the United States moves toward more sustainable and renewable sources of energy, hydropower is expected to play a pivotal role in integrating more intermittent renewables like wind and solar to the electricity grid