Progress, and Applications
of the Human Genome Project
Sponsored by the U.S. Department of Energy Human Genome Program
Human Genome News Archive Edition
Human Genome News, January 1998; 9:(1-2)
In July 1997, researchers reported the construction of a high-resolution physical map for human chromosome 7 [Genome Research 7(7), 673-92]. With an average STS spacing of about 79 kb, the new map exceeds the Human Genome Project goal and provides a framework for future chromosome 7 sequencing. The map, which covers virtually all the 170-Mb chromosome, was built using a YAC-based, STS-content approach and includes 22 YAC contigs integrated with the genetic, radiation hybrid, and cytogenetic maps generated for that chromosome.
Collaborators on the project included a team led by Eric Green at the NIH National Human Genome Research Institute and researchers at the Washington University School of Medicine (St. Louis), Gënëthon (France), and the University of Washington. [Information: http://research.nhgri.nih.gov/chr7/]
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