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Mass Spectrometry and Laser Spectroscopy Group Core Capabilities

Topic:
  • Laser ablation inductively coupled plasma mass spectrometry elemental imaging
  • Hybrid optical microscopy/laser ablation liquid capture electrospray ionization mass spectrometry imaging
  • Hybrid atomic force microscopy/mass spectrometry platforms for physical and chemical   imaging
  • Liquid extraction based spatially resolved surface analysis for rapid and sensitive profiling of biologically important surfaces
  • Nonlinear and multimodal optical imaging methods to study energy and charge flow in materials
  • Surface specific spectroscopies for the analysis of equilibrium and dynamics processes at surfaces
  • Widefield nonlinear imaging methods for the study of thin film structure and nanomaterial interfaces
  • Multi-dimensional liquid chromatography-tandem mass spectrometry capabilities for complex proteome measurements
  • Technology platforms for environmental metaproteome measurements, ranging from high throughput to high performance systems.
  • Global and targeted proteome measurement approaches for microbial and plant/human host systems.
  • Advanced bioinformatic pipelines to process raw MS data and integrate with other systems biology omics datasets.
Leica laser microdissection system LMD7000 used in hybrid system for co-registered optical microscopy and mass spectrometry imaging
ESI Laser Ablation NWR 193 system coupled with Thermo iCAP Q Inductively Coupled Plasma Mass Spectrometer for elemental imaging
Dionex HPLC interfaced via nanoelectrospray with Thermo LTQ Orbitrap Elite mass spectrometer for proteomic analyses