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A flow cytometry-based dopamine transporter binding assay using antagonist-conjugated quantum dots ...

by Oleg Kovtun, Emily Ross, Ian Tomlinson, Sandra J Rosenthal
Publication Type
Journal
Journal Name
Chemical Communications
Publication Date
Page Numbers
5426 to 5430
Volume
48
Issue
44

Here we present the development and validation of a flow
cytometry-based dopamine transporter (DAT) binding assay
that uses antagonist-conjugated quantum dots (QDs).We anticipate
that our QD-based assay is of immediate value to the high
throughput screening of novel DAT modulators.