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Interfacial tension controlled fusion of individual femtoliter droplets and triggering of confined chemical reactions on dema...

by Charles P Collier, Seung-yong Jung, Scott T Retterer
Publication Type
Journal
Journal Name
Lab on a Chip
Publication Date
Page Numbers
3373 to 3376
Volume
10
Issue
24

This paper describes stepwise, on-demand generation and fusion of femtoliter aqueous droplets based on interfacial tension. Sub-millisecond mixing times from droplet fusion were demonstrated, as well as a reversible chemical toggle switch based on alternating fusion of droplets containing acidic or basic solution, monitored with the pH-dependent emission of fluorescein.