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Metabolome-Proteome Differentiation Coupled to Microbial Divergence...

Publication Type
Journal
Journal Name
mBio
Publication Date
Page Numbers
1 to 5
Volume
1
Issue
5

Tandem high-throughput proteomics and metabolomics were employed to functionally characterize natural microbial
biofilm communities. Distinct molecular signatures exist for each analyzed sample. Deconvolution of the high-resolution
molecular data demonstrates that identified proteins and detected metabolites exhibit organism-specific correlation patterns.
These patterns are reflective of the functional differentiation of two bacterial species that share the same genus and that co-occur
in the sampled microbial communities. Our analyses indicate that the two species have similar niche breadths and are not in
strong competition with one another.