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Phenyleneethynylene trimer-based rigid-flexible [2+2] macrocycles for nucleic acid labelling in live cells...

Publication Type
Journal
Journal Name
Chemical Communications
Publication Date
Page Numbers
5930 to 5933
Volume
55
Issue
42

Fluorescent macromolecules were developed for intracellular labeling in live cells. Coupling rigid rod phenyleneethynylene trimers with flexible amphiphilic diamines via the imine-bond formation chemistry yielded rigid–flexible [2+2] macromolecules showing nucleic acid selectivity and nontoxicity in live cells.