Progress, and Applications
of the Human Genome Project
Sponsored by the U.S. Department of Energy Human Genome Program
Human Genome News Archive Edition
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Breast Cancer Researchers Use Gene Expressions
Using gene-expression profiling, an international group of researchers led by Jeffrey Trent (NIH National Human Genome Research Institute) has made it possible to distinguish between hereditary and sporadic breast tumors for the first time. Simultaneous microarray assessments of some 6000 genes within breast cancer cells revealed clear and unique differences in activity patterns, leading to a new test that shows exactly which genes are active in a tumor cell. This capability may have important implications for both diagnosis and treatment. The findings were published in the New England Journal of Medicine 344(8), 539 48 (February 22, 2001).
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Last modified: Wednesday, October 29, 2003
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