![Eugene Dumitrescu, Ben Lawrie, Matthew Feldman, and Jordan Hachtel (from left) have conducted investigations aimed at controlling the dissipative nature of quantum systems and materials. The cathodoluminescence microscope used in their work appears at rig Eugene Dumitrescu, Ben Lawrie, Matthew Feldman, and Jordan Hachtel (from left) have conducted investigations aimed at controlling the dissipative nature of quantum systems and materials. The cathodoluminescence microscope used in their work appears at rig](/sites/default/files/styles/list_page_thumbnail/public/Quantum%20physics%20main%20photo%5B1%5D_0.jpg?itok=Y67Yqnmc)
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![Eugene Dumitrescu, Ben Lawrie, Matthew Feldman, and Jordan Hachtel (from left) have conducted investigations aimed at controlling the dissipative nature of quantum systems and materials. The cathodoluminescence microscope used in their work appears at rig Eugene Dumitrescu, Ben Lawrie, Matthew Feldman, and Jordan Hachtel (from left) have conducted investigations aimed at controlling the dissipative nature of quantum systems and materials. The cathodoluminescence microscope used in their work appears at rig](/sites/default/files/styles/list_page_thumbnail/public/Quantum%20physics%20main%20photo%5B1%5D_0.jpg?itok=Y67Yqnmc)
![Using neutrons, an ORNL research team studied the protein structure of bacteria-produced enzymes called beta-lactamases by examining one of them to better understand how resistant bacteria behave. Using neutrons, an ORNL research team studied the protein structure of bacteria-produced enzymes called beta-lactamases by examining one of them to better understand how resistant bacteria behave.](/sites/default/files/styles/list_page_thumbnail/public/news/images/Neutrons-Antibacterial_breakdown_2.png?itok=KciUjook)
![Oak Ridge National Laboratory bioinformatics researcher Dan Jacobson plugs AI, deep learning into biosystems. Oak Ridge National Laboratory bioinformatics researcher Dan Jacobson plugs AI, deep learning into biosystems.](/sites/default/files/styles/list_page_thumbnail/public/DanJacobson.jpg?itok=39-Nscun)
Dan Jacobson is illuminating the workings of biological systems from the molecular scale up by leveraging Oak Ridge National Laboratory’s supercomputing resources to create machine- and deep-learning techniques more easily understood by humans
![The hCA II active site is flanked by hydrophilic (violet) and hydrophobic (green) binding pockets that can be used to design specific drugs targeting cancer-associated hCAs. Five clinical drugs are shown superimposed in the hCA II active site The hCA II active site is flanked by hydrophilic (violet) and hydrophobic (green) binding pockets that can be used to design specific drugs targeting cancer-associated hCAs. Five clinical drugs are shown superimposed in the hCA II active site](/sites/default/files/styles/list_page_thumbnail/public/hCA_overall%5B2%5D.png?itok=_C9a87FK)
New insights from neutron analysis of glaucoma drugs and their enzyme target may help scientists design drugs that more effectively target aggressive cancers.
![Oak Ridge National Laboratory bioinformatics researcher Dan Jacobson plugs AI, deep learning into biosystems. Oak Ridge National Laboratory bioinformatics researcher Dan Jacobson plugs AI, deep learning into biosystems.](/sites/default/files/styles/list_page_thumbnail/public/DanJacobson.jpg?itok=39-Nscun)
![The hCA II active site is flanked by hydrophilic (violet) and hydrophobic (green) binding pockets that can be used to design specific drugs targeting cancer-associated hCAs. Five clinical drugs are shown superimposed in the hCA II active site The hCA II active site is flanked by hydrophilic (violet) and hydrophobic (green) binding pockets that can be used to design specific drugs targeting cancer-associated hCAs. Five clinical drugs are shown superimposed in the hCA II active site](/sites/default/files/styles/list_page_thumbnail/public/hCA_overall%5B2%5D_0.png?itok=UEpJXtYj)
![The hCA II active site is flanked by hydrophilic (violet) and hydrophobic (green) binding pockets that can be used to design specific drugs targeting cancer-associated hCAs. Five clinical drugs are shown superimposed in the hCA II active site The hCA II active site is flanked by hydrophilic (violet) and hydrophobic (green) binding pockets that can be used to design specific drugs targeting cancer-associated hCAs. Five clinical drugs are shown superimposed in the hCA II active site](/sites/default/files/styles/list_page_thumbnail/public/hCA_overall%5B2%5D_0.png?itok=UEpJXtYj)
New insights from neutron analysis of glaucoma drugs and their enzyme target may help scientists design drugs that more effectively target aggressive cancers.
![BraundmeierA_SIU_ORNL BraundmeierA_SIU_ORNL](/sites/default/files/styles/list_page_thumbnail/public/BraundmeierA_0011_0.jpg?itok=--Bxi4IU)
![ORNL Image](/sites/default/files/styles/list_page_thumbnail/public/INCITE%20graphic.png?itok=UwWr_aLQ)
A cross-disciplinary research team at Oak Ridge National Laboratory is using supercomputing to create an unprecedented view of the 3D interactions among components of the cellular machinery in Populus trichocarpa (black cottonwood)
![BraundmeierA_SIU_ORNL BraundmeierA_SIU_ORNL](/sites/default/files/styles/list_page_thumbnail/public/BraundmeierA_0011_0.jpg?itok=--Bxi4IU)