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![ORNL scientists developed a method that improves the accuracy of the CRISPR Cas9 gene editing tool used to modify microbes for renewable fuels and chemicals production. This research draws on the lab’s expertise in quantum biology, artificial intelligence and synthetic biology. Credit: Philip Gray/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2023-11/CRISPR%20Quantum%20AI_2_23-G07105-DOE-BER-BESSD-comms-graphic-pcg_2.jpg?h=847b7ff0&itok=WD2dBsAC)
Scientists at ORNL used their expertise in quantum biology, artificial intelligence and bioengineering to improve how CRISPR Cas9 genome editing tools work on organisms like microbes that can be modified to produce renewable fuels and chemicals.
![Hilda Klasky](/sites/default/files/styles/list_page_thumbnail/public/2023-11/Hilda%20Klasky.jpg?h=dbae05b8&itok=CPlpl2-D)
Hilda Klasky, an R&D staff member in the Scalable Biomedical Modeling group at ORNL, has been selected as a senior member of the Association of Computing Machinery, or ACM.
![Seeing the difference Ac-225 could make to cancer patients made Raina Setzer want to come to ORNL to directly work with the isotope. Credit: Allison Peacock/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2023-11/rs_0.jpg?h=71976bb4&itok=nFsgqwUT)
Raina Setzer knows the work she does matters. That’s because she’s already seen it from the other side. Setzer, a radiochemical processing technician in Oak Ridge National Laboratory’s Isotope Processing and Manufacturing Division, joined the lab in June 2023.
![: This schematic of tokamak core-pedestal-boundary regions show what will be simulated by an ORNL project applying machine learning to plasma physics modeling. Credit: Giacomin et al., J. Comput. Phys., 463, (2022) 111294, https://doi.org/10.1016/j.jcp.2022.11294](/sites/default/files/styles/list_page_thumbnail/public/2023-10/Fusion%20tokamak%20simulator.png?h=e1e3aba4&itok=kiVnri5A)
ORNL will lead three new DOE-funded projects designed to bring fusion energy to the grid on a rapid timescale.
![HFIR](/sites/default/files/styles/list_page_thumbnail/public/2020-04/HFIR_0.jpg?h=56d0ca2e&itok=8tMcVdaT)
Creating energy the way the sun and stars do — through nuclear fusion — is one of the grand challenges facing science and technology. What’s easy for the sun and its billions of relatives turns out to be particularly difficult on Earth.
![TIP graphic](/sites/default/files/styles/list_page_thumbnail/public/2023-06/TIPbg_1200.png?h=da33fe38&itok=y7ggwHLV)
Scientist-inventors from ORNL will present seven new technologies during the Technology Innovation Showcase on Friday, July 14, from 8 a.m.–4 p.m. at the Joint Institute for Computational Sciences on ORNL’s campus.
![The Fuel Pellet Fueling Laboratory at ORNL is part of a suite of fusion energy R&D capabilities and provides test equipment and related diagnostics for carrying out experiments to develop pellet injectors for plasma fueling applications. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2023-06/2021-P02876_0.jpg?h=c6980913&itok=8fqWlX5k)
ORNL will team up with six of eight companies that are advancing designs and research and development for fusion power plants with the mission to achieve a pilot-scale demonstration of fusion within a decade.
![Phil Snyder](/sites/default/files/styles/list_page_thumbnail/public/2023-04/snyder.png?h=17c3cd98&itok=1HuorVwS)
When virtually unlimited energy from fusion becomes a reality on Earth, Phil Snyder and his team will have had a hand in making it happen.
![Mickey Wade](/sites/default/files/styles/list_page_thumbnail/public/2023-03/2022-P03120.jpg?h=8f9cfe54&itok=w-IR0uZ1)
Mickey Wade has been named associate laboratory director for the Fusion and Fission Energy and Science Directorate at the Department of Energy’s Oak Ridge National Laboratory, effective April 1.
![Samantha Peters co-designed and conducted experiments using ORNL’s high-performance mass spectrometry techniques to prove that bacteriophages deploy genetic code-switching to overwhelm and destroy host bacteria. Credit: Genevieve Martin, ORNL/U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2023-03/2023-P00717_0.jpg?h=2b2da530&itok=Ae7uW6ug)
Scientists at ORNL have confirmed that bacteria-killing viruses called bacteriophages deploy a sneaky tactic when targeting their hosts: They use a standard genetic code when invading bacteria, then switch to an alternate code at later stages of