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This protein drives key processes for sulfide use in many microorganisms that produce methane, including Thermosipho melanesiensis. Researchers used supercomputing and deep learning tools to predict its structure, which has eluded experimental methods such as crystallography. Credit: Ada Sedova/ORNL, U.S. Dept. of Energy

Scientists use Summit supercomputer, deep learning to predict protein functions at genome scale

A team of scientists led by the Department of Energy’s Oak Ridge National Laboratory and the Georgia Institute of Technology is using supercomputing and revolutionary deep learning tools to predict the structures and roles of thousands of proteins with unknown functions.

Using quantum Monte Carlo methods, the researchers simulated bulk VO2. Yellow and turquoise represent changes in electron density between the excited and ground states of a compound composed of oxygen, in red, and vanadium, in blue, which allowed them to evaluate how an oxygen vacancy, in white, can alter the compound’s properties. Credit: Panchapakesan Ganesh/ORNL, U.S. Dept. of Energy

Artificially altered material could accelerate neuromorphic device development

Neuromorphic devices — which emulate the decision-making processes of the human brain — show great promise for solving pressing scientific problems, but building physical systems to realize this potential presents researchers with a significant

ORNL researchers proved that COVID-19 vaccines can be kept ultra-cool for an extended period in a retrofitted commercial storage container, providing a resource for safe delivery to remote locations. Credit: ORNL, U.S. Dept. of Energy

Refrigeration — Cooling COVID-19 vaccines

Oak Ridge National Laboratory researchers have retrofitted a commercial refrigeration container designed to ensure COVID-19 vaccines remain at ultra-low temperatures during long transport and while locally stored.

ORNL is making underused or inaccessible bioenergy data available to accelerate innovation for the bioeconomy. Credit: Andy Sproles/ORNL, U.S. Dept. of Energy

Bioenergy — Data boost

A research team from Oak Ridge National Laboratory has identified and improved the usability of data that can help accelerate innovation for the growing bioeconomy.

ORNL’s Eva Zarkadoula seeks piezoelectric materials for sensors that can withstand irradiation, which causes cascading collisions that displace atoms and produces defects. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

Materials — Radiation-resistant sensors

To advance sensor technologies, Oak Ridge National Laboratory researchers studied piezoelectric materials, which convert mechanical stress into electrical energy, to see how they could handle bombardment with energetic neutrons.

This section of a serpentine channel reactor shows the parallel reactor and feeder channels separated by a nanoporous membrane. At left is a single nanopore viewed from the side; at right is a diagram of metabolite exchange across the membrane.

ORNL cell-free protein synthesis is potential lifesaver

Lives of soldiers and others injured in remote locations could be saved with a cell-free protein synthesis system developed at the Department of Energy’s Oak Ridge National Laboratory. The device, a creation of a team led by Andrea Timm and Scott Retterer of the ...
By producing 50 grams of plutonium-238, Oak Ridge National Laboratory researchers have demonstrated the nation’s ability to provide a valuable energy source for deep space missions.

ORNL achieves milestone with plutonium-238 sample

With the production of 50 grams of plutonium-238, researchers at the Department of Energy’s Oak Ridge National Laboratory have restored a U.S. capability dormant for nearly 30 years and set the course to provide power for NASA and other missions.

In situ neutron diffraction visualizes the synthesis mechanism, involving multi-phase evolutions, of garnet-type fast lithium-ion solid conductors. The neutron diffraction determines the lithium vacancy distribution in the garnet lattice, and reveals the

Neutrons offer guide to getting more out of solid-state lithium-ion batteries

Although they don’t currently have as much conductivity, solid-state electrolytes designed for lithium-ion batteries (LIBs) are emerging as a safer alternative to their more prevalent—sometimes flammable—liquid-electrolyte counterparts. However, a new study conducted at Oak Ridg...
The Roane State Community College associates are (from left) Jeff Manning, Chris Zerr, Bruce Lester, Joe Pyle, Darrell Roddy and Rusty Dryman.

Mapping a future

Bruce Lester has had a lot of jobs: fisherman, horse trainer, “professional stair builder.” He last worked for a real estate company, surveying land using geographic software. “When the bottom fell out of the construction industry and the company downsized, I got laid off,” 

Sheng Dai of the Department of Energy’s Oak Ridge National Laboratory.

ORNL’s Dai ranked among world’s most influential scientists

Sheng Dai of the Department of Energy’s Oak Ridge National Laboratory has been named to a list of the most highly cited researchers in the world. Thomson Reuters Highly Cited Researchers is an annual list that recognizes some of the world’s leading