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Since the discovery of high-temperature superconductors — materials that can transport electricity with perfect efficiency at or near liquid nitrogen temperatures (minus-196 degrees Celsius) — scientists have been working to develop a theory that explains their essential physics.
In pure water, lignin adopts a globular conformation (left) that aggregates on cellulose and blocks enzymes. In a THF-water cosolvent, lignin adopts coil conformations that are easier to remove during pretreatment. (ORNL image)
Breaking down cellulosic biomass for biofuel is a costly and complex process, requiring lots of acid, water, and heat. Experimental pretreatments, however, hold the promise of driving down these costs by making more biomass available to enzymes for fermentation. To gain a better...