Quantum precision reached in modeling molten salt behavior
Scientists at Oak Ridge National Laboratory have uncovered how the SARS-CoV-2 virus evades the human immune system by studying the interaction between a viral protein (PLpro) and a key immune protein (ISG15). These insights could guide the development of therapeutic drugs to block this interaction, enhancing the body’s ability to combat the virus.
An ORNL-led team comprising researchers from multiple DOE national laboratories is using artificial intelligence and computational screening techniques – in combination with experimental validation – to identify and design five promising drug therapy approaches to target the SARS-CoV-2 virus.
The Department of Energy’s Office of Science has selected five Oak Ridge National Laboratory scientists for Early Career Research Program awards.
From Denmark to Japan, the UK, France, and Sweden, physicist Ken Andersen has worked at neutron sources around the world. With significant contributions to neutron scattering and the scientific community, he’s now serving in his most important role yet.
When COVID-19 was declared a pandemic in March 2020, Oak Ridge National Laboratory’s Parans Paranthaman suddenly found himself working from home like millions of others.
Scientists have found new, unexpected behaviors when SARS-CoV-2 – the virus that causes COVID-19 – encounters drugs known as inhibitors, which bind to certain components of the virus and block its ability to reproduce.
Ken Andersen has been named associate laboratory director for the Neutron Sciences Directorate, or NScD, at the Department of Energy’s Oak Ridge National Laboratory.
Researchers believe that proteins could behave differently in lipid raft environments, compared to non-raft regions in a membrane, but this hypothesis has not been fully evaluated. One reason is that membrane models used to study membrane proteins rarely contain rafts.
The ExOne Company, the global leader in industrial sand and metal 3D printers using binder jetting technology, announced it has reached a commercial license agreement with Oak Ridge National Laboratory to 3D print parts in aluminum-infiltrated boron carbide.
The COHERENT particle physics experiment at the Department of Energy’s Oak Ridge National Laboratory has firmly established the existence of a new kind of neutrino interaction.