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Hugh O’Neill’s lifelong fascination with the complexities of the natural world drives his research at ORNL, where he’s using powerful neutron beams to dive deep into the microscopic realm of biological materials and unlock secrets for better production of domestic biofuels and bioproducts.

Scientists conducted a groundbreaking study on the genetic data of over half a million U.S. veterans, using tools from the Oak Ridge National Laboratory to analyze 2,068 traits from the Million Veteran Program.

Researchers used the world’s fastest supercomputer, Frontier, to train an AI model that designs proteins, with applications in fields like vaccines, cancer treatments, and environmental bioremediation. The study earned a finalist nomination for the Gordon Bell Prize, recognizing innovation in high-performance computing for science.

The Proton Power Upgrade project at ORNL's Spallation Neutron Source has achieved its final key performance parameter of 1,250 hours of neutron production at 1.7 megawatts of proton beam power on a newly developed target.

A team of researchers used the Frontier supercomputer and a new methodology for conducting a genome-wide association study to earn a finalist nomination for the Association for Computing Machinery’s 2024 Gordon Bell Prize for outstanding

Researchers used the Summit supercomputer at ORNL to answer one of fission’s big questions: What exactly happens during the nucleus’s “neck rupture” as it splits in two? Scission neutrons have been theorized to be among those particles emitted during neck rupture, although their exact characteristics have been debated due to a lack of conclusive experimental evidence of their existence.

Researchers led by the University of Melbourne, Australia, have been nominated for the Association for Computing Machinery’s 2024 Gordon Bell Prize in supercomputing for conducting a quantum molecular dynamics simulation 1,000 times greater in size and speed than any previous simulation of its kind.

Biochemist David Baker — just announced as a recipient of the Nobel Prize for Chemistry — turned to the High Flux Isotope Reactor (HFIR) at Oak Ridge National Laboratory for information he couldn’t get anywhere else. HFIR is the strongest reactor-based neutron source in the United States.

Scientists at ORNL used neutrons to end a decades-long debate about an enzyme cancer uses.

ORNL's Spallation Neutron Source, the nation’s leading source of pulsed neutron beams for research, was recently restarted after nine months of upgrade work.