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Analyses of lung fluid cells from COVID-19 patients conducted on the nation’s fastest supercomputer point to gene expression patterns that may explain the runaway symptoms produced by the body’s response to SARS-CoV-2. Credit: Jason B. Smith/ORNL, U.S. Dept. of Energy

A team led by Dan Jacobson of Oak Ridge National Laboratory used the Summit supercomputer at ORNL to analyze genes from cells in the lung fluid of nine COVID-19 patients compared with 40 control patients.

The protease protein is both shaped like a heart and functions as one, allowing the virus replicate and spread. Inhibiting the protease would block virus reproduction. Credit: Andrey Kovalevsky/ORNL, U.S. Dept. of Energy

A team of researchers has performed the first room-temperature X-ray measurements on the SARS-CoV-2 main protease — the enzyme that enables the virus to reproduce.

ORNL welcomes six new research fellows to Innovation Crossroads

ORNL welcomed six technology innovators to join the fourth cohort of Innovation Crossroads, the Southeast’s only entrepreneurial research and development program based at a U.S. Department of Energy national laboratory.

Coronavirus research

Researchers at the Department of Energy’s Oak Ridge National Laboratory have used Summit, the world’s most powerful and smartest supercomputer, to identify 77 small-molecule drug compounds that might warrant further study in the fight

ORNL's Battery Manufacturing Facility

Energy storage startup SPARKZ Inc. has exclusively licensed five battery technologies from the Department of Energy’s Oak Ridge National Laboratory designed to eliminate cobalt metal in lithium-ion batteries. The advancement is aimed at accelerating the production of electric vehicles and energy storage solutions for the power grid.

St John's CyberForce team

Oak Ridge National Laboratory will give college students the chance to practice cybersecurity skills in a real-world setting as a host of the Department of Energy’s fifth collegiate CyberForce Competition on Nov. 16. The event brings together student teams from across the country to compete at 10 of DOE’s national laboratories.

CellSight allows for rapid mass spectrometry of individual cells. Credit: John Cahill, Oak Ridge National Laboratory/U.S. Dept of Energy

Researchers at the Department of Energy’s Oak Ridge National Laboratory have received five 2019 R&D 100 Awards, increasing the lab’s total to 221 since the award’s inception in 1963.

Representatives from The University of Toledo and the U.S. Department of Energy’s Oak Ridge National Laboratory (ORNL) in Tennessee are teaming up to conduct collaborative automotive materials research.” Credit: University of Toledo

ORNL and The University of Toledo have entered into a memorandum of understanding for collaborative research.

Summit supercomputer

Processes like manufacturing aircraft parts, analyzing data from doctors’ notes and identifying national security threats may seem unrelated, but at the U.S. Department of Energy’s Oak Ridge National Laboratory, artificial intelligence is improving all of these tasks.

quantum mechanics to advance a range of technologies including computing, fiber optics and network communication

Three researchers at Oak Ridge National Laboratory will lead or participate in collaborative research projects aimed at harnessing the power of quantum mechanics to advance a range of technologies including computing, fiber optics and network