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Hugh O'Neil, director or ORNL's Center for Structural Molecular Biology is sitting in the lab on a stool, hand on desk with glasses on. There are lab related items blurred in the foreground.

Hugh O’Neill’s lifelong fascination with the complexities of the natural world drives his research at ORNL, where he’s using powerful neutron beams to dive deep into the microscopic realm of biological materials and unlock secrets for better production of domestic biofuels and bioproducts.

the foreground shows new macromolecules that could be made using a process invented by Oak Ridge National Laboratory chemists to upcycle the polymers from discarded plastics.

By editing the polymers of discarded plastics, ORNL chemists have found a way to generate new macromolecules with more valuable properties than those of the starting material.

ORNL researcher Melissa Cregger is standing outside smiling for a photo. Woman is wearing blue and white polka dot shirt with a purple cardigan.

Melissa Cregger of the Department of Energy’s Oak Ridge National Laboratory has received the Presidential Early Career Award for Science and Engineers, or PECASE, the highest honor bestowed by the U.S. government on outstanding early-career scientists and engineers. 

Procter & Gamble scientists used ORNL’s Summit supercomputer to create a digital model of the corneal epithelium, the primary outer layer of cells covering the human eye, and test that model against a series of cleaning compounds in search of a gentler, more environmentally sustainable formula.

P&G is using simulations on the ORNL Summit supercomputer to study how surfactants in cleaners cause eye irritation. By modeling the corneal epithelium, P&G aims to develop safer, concentrated cleaning products that meet performance and safety standards while supporting sustainability goals.

Two pictures of a rounded triangle shape are shown in mirror image. The left is white with red and purple spots in the middle while the one on the right is purple with a yellow and blue ring in the middle

Scientists designing the world’s first controlled nuclear fusion power plant, ITER, needed to solve the problem of runaway electrons, negatively charged particles in the soup of matter in the plasma within the tokamak, the magnetic bottle intended to contain the massive energy produced. Simulations performed on Summit, the 200-petaflop supercomputer at ORNL, could offer the first step toward a solution.

ORNL chemist Benjamin Manard is posing for a photo with a light blue and navy background

Benjamin Manard, a nuclear analytical chemist at ORNL, has been named the 2025 winner of the Emerging Leader in Atomic Spectroscopy Award from Spectroscopy magazine. 

ORNL’s Askin Guler Yigitoglu presents during the 2024 Molten Salt Reactor Workshop in Knoxville with a green and blue background

ORNL’s annual workshop has become the premier forum for molten salt reactor, or MSR, collaboration and innovation, convening industry, academia and government experts to further advance MSR research and development. This year’s event attracted a record-breaking 365 participants from across the country, highlighting the momentum to bring MSRs online.

A picture containing indoor, equipment, control panel

A research partnership between two Department of Energy national laboratories has accelerated inspection of additively manufactured nuclear components, and the effort is now expanding to inspect nuclear fuels. 

Photo is a high aerial view of lake superior through the clouds

Researchers at Stanford University, the European Center for Medium-Range Weather Forecasts, or ECMWF, and ORNL used the lab’s Summit supercomputer to better understand atmospheric gravity waves, which influence significant weather patterns that are difficult to forecast. 

Picture shows magnetic domains in uranium with a blue and orange organic shapes, similar to lava flowing through water, but in graphic form

The US focuses on nuclear nonproliferation, and ORNL plays a key role in this mission. The lab conducts advanced research in uranium science, materials analysis and nuclear forensics to detect illicit nuclear activities. Using cutting-edge tools and operational systems, ORNL supports global efforts to reduce nuclear threats by uncovering the history of nuclear materials and providing solutions for uranium removal.