Skip to main content
Graphic representation of ai model that identifies proteins

Researchers used the world’s fastest supercomputer, Frontier, to train an AI model that designs proteins, with applications in fields like vaccines, cancer treatments, and environmental bioremediation. The study earned a finalist nomination for the Gordon Bell Prize, recognizing innovation in high-performance computing for science.

Eugene P. Wigner Fellow Huan Zhao working in his lab

Huan Zhao, a Eugene P. Wiger Fellow at ORNL, focuses on advancing quantum materials and information technologies, inspired by his grandfather's passion for education. His research in energy-efficient memory devices and sensitive quantum light sources reflects his commitment to scientific progress and education equity.

A photo of the inside of a cabinet for the Frontier supercomputer at ORNL

A team of researchers used the Frontier supercomputer and a new methodology for conducting a genome-wide association study to earn a finalist nomination for the Association for Computing Machinery’s 2024 Gordon Bell Prize for outstanding

Pictured is a 3D printed roosting structure for bats.

Oak Ridge National Laboratory researchers are using a new bioderived material to 3D print custom roosting structures for endangered bats.

Image of Giuseppe Barca looking at two computer monitors, representing the team using Frontier to perform the first quantum chemistry calculations to exceed an exaflop.

Researchers led by the University of Melbourne, Australia, have been nominated for the Association for Computing Machinery’s 2024 Gordon Bell Prize in supercomputing for conducting a quantum molecular dynamics simulation 1,000 times greater in size and speed than any previous simulation of its kind.

An image depicting the process of parallel quantum-enhanced sensing

Researchers from ORNL have taken a major step forward in using quantum mechanics to enhance sensing devices, a new advancement that could be used in a wide range of areas, including materials characterization, improved imaging and biological and medical applications.

Pictured is the IMAGINE instrument at the High Flux Isotope Reactor

Biochemist David Baker — just announced as a recipient of the Nobel Prize for Chemistry — turned to the High Flux Isotope Reactor (HFIR) at Oak Ridge National Laboratory for information he couldn’t get anywhere else. HFIR is the strongest reactor-based neutron source in the United States.  

Larry York is sitting in front of a computer screen showing an image of plant phenotyping

The Advanced Plant Phenotyping Laboratory at ORNL utilizes robotics, multi-modal imaging, and AI to enhance understanding of plant genetics and interactions with microbes. It aims to connect genes to traits for advancements in bioenergy, agriculture, and climate resilience. Senior scientist Larry York highlights the lab's capabilities and the insights from a new digital underground imaging system to improve biomass feedstocks for bioenergy and carbon storage.

Graphic of Jordan Cannon

Jordan Cannon is CEO of Circular Biosciences, a Cohort 2024 Innovation Crossroads company, a startup dedicated to accelerating bioplastic degradation for more widespread use, easier disposal and reduced environmental impact. 

Illustration of a hydrogen atom.

Scientists at ORNL used neutrons to end a decades-long debate about an enzyme cancer uses.