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Different groups of proteins shown in different colors combine and attach to a broken strand of DNA.

Researchers at Georgia State University used the Summit supercomputer to study an elaborate molecular pathway called nucleotide excision repair. Decoding NER’s sophisticated sequence of events and the role of PInC in the pathway could provide key insights into developing novel treatments and preventing conditions that lead to premature aging and certain types of cancer.

Secretary Wright leans over red computer door, signing with silver sharpie as ORNL Director Stephen Streiffer looks on

During his first visit to Oak Ridge National Laboratory, Energy Secretary Chris Wright compared the urgency of the Lab’s World War II beginnings to today’s global race to lead in artificial intelligence, calling for a “Manhattan Project 2.”

Six images fanned out across the right side of the page with the first page showcasing the report cover. To the right hand side is a green oak leaf.

A workshop led by scientists at ORNL sketched a road map toward a longtime goal: development of autonomous, or self-driving, next-generation research laboratories. 

the foreground shows new macromolecules that could be made using a process invented by Oak Ridge National Laboratory chemists to upcycle the polymers from discarded plastics.

By editing the polymers of discarded plastics, ORNL chemists have found a way to generate new macromolecules with more valuable properties than those of the starting material.

ORNL researcher Melissa Cregger is standing outside smiling for a photo. Woman is wearing blue and white polka dot shirt with a purple cardigan.

Melissa Cregger of the Department of Energy’s Oak Ridge National Laboratory has received the Presidential Early Career Award for Science and Engineers, or PECASE, the highest honor bestowed by the U.S. government on outstanding early-career scientists and engineers. 

Procter & Gamble scientists used ORNL’s Summit supercomputer to create a digital model of the corneal epithelium, the primary outer layer of cells covering the human eye, and test that model against a series of cleaning compounds in search of a gentler, more environmentally sustainable formula.

P&G is using simulations on the ORNL Summit supercomputer to study how surfactants in cleaners cause eye irritation. By modeling the corneal epithelium, P&G aims to develop safer, concentrated cleaning products that meet performance and safety standards while supporting sustainability goals.

ORNL chemist Benjamin Manard is posing for a photo with a light blue and navy background

Benjamin Manard, a nuclear analytical chemist at ORNL, has been named the 2025 winner of the Emerging Leader in Atomic Spectroscopy Award from Spectroscopy magazine. 

ORNL researcher Phong Le poses for a photo outside on a walkway bridge over the pond. The photo is framed with brown and green plants

Phong Le is a computational hydrologist at ORNL who is putting his skills in hydrology, numerical modeling, machine learning and high-performance computing to work quantifying water-related risks for humans and the environment. 

Image is blue and green with the background being a building on the left, merging into the photo on the right which are pictures of doppler radar graphics

Researchers at the Department of Energy’s Oak Ridge National Laboratory are using non-weather data from the nationwide weather radar network to understand how to track non-meteorological events moving through the air for better emergency response. 

Man is flying drone in hurricane aftermath, holding the controller

During Hurricanes Helene and Milton, ORNL deployed drone teams and the Mapster platform to gather and share geospatial data, aiding recovery and damage assessments. ORNL's EAGLE-I platform tracked utility outages, helping prioritize recovery efforts. Drone data will train machine learning models for faster damage detection in future disasters.