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Researchers at Georgia State University used the Summit supercomputer to study an elaborate molecular pathway called nucleotide excision repair. Decoding NER’s sophisticated sequence of events and the role of PInC in the pathway could provide key insights into developing novel treatments and preventing conditions that lead to premature aging and certain types of cancer.

During his first visit to Oak Ridge National Laboratory, Energy Secretary Chris Wright compared the urgency of the Lab’s World War II beginnings to today’s global race to lead in artificial intelligence, calling for a “Manhattan Project 2.”

A workshop led by scientists at ORNL sketched a road map toward a longtime goal: development of autonomous, or self-driving, next-generation research laboratories.

Not only did ORNL take home top honors at the 2024 International Conference for High Performance Computing, Networking, Storage, and Analysis (SC24), but the lab’s computing staff also shared career advice and expertise with students eager to enter the world of supercomputing.

Hugh O’Neill’s lifelong fascination with the complexities of the natural world drives his research at ORNL, where he’s using powerful neutron beams to dive deep into the microscopic realm of biological materials and unlock secrets for better production of domestic biofuels and bioproducts.

Melissa Cregger of the Department of Energy’s Oak Ridge National Laboratory has received the Presidential Early Career Award for Science and Engineers, or PECASE, the highest honor bestowed by the U.S. government on outstanding early-career scientists and engineers.

P&G is using simulations on the ORNL Summit supercomputer to study how surfactants in cleaners cause eye irritation. By modeling the corneal epithelium, P&G aims to develop safer, concentrated cleaning products that meet performance and safety standards while supporting sustainability goals.

Scientists designing the world’s first controlled nuclear fusion power plant, ITER, needed to solve the problem of runaway electrons, negatively charged particles in the soup of matter in the plasma within the tokamak, the magnetic bottle intended to contain the massive energy produced. Simulations performed on Summit, the 200-petaflop supercomputer at ORNL, could offer the first step toward a solution.

Phong Le is a computational hydrologist at ORNL who is putting his skills in hydrology, numerical modeling, machine learning and high-performance computing to work quantifying water-related risks for humans and the environment.

ORNL’s annual workshop has become the premier forum for molten salt reactor, or MSR, collaboration and innovation, convening industry, academia and government experts to further advance MSR research and development. This year’s event attracted a record-breaking 365 participants from across the country, highlighting the momentum to bring MSRs online.