In this issue...
HGP on Fast Track
Joint Genome Institute Exceeds Goal
Sequencing with BACs
with STCs and STSs
of BAC Clones and STC Data
Resource Success Story
Hunt SNPs for Variation, Disease
Sequencing the Human Genome?
Progress in Science
Promotes Remote Access to Instrumentation
Private-Sector Sequencing Project
In the News
Delivers C. elegans Sequence
Sequence Entire Genomes? Worm's Eye View
BER Research Update
1998 Human Genome Awards Announced
Consortium for Functional Genomics
Merges Offices, Web Sites
Microbial Genomes Searchable
Releases Chlorobium tepidum Sequence
MGP Abstracts Online
Ethical, Legal, and Social Issues
and Educational Resources
Lander, Genetics in the 21st Century
Rothstein, Genetic Privacy
Wilson, Gene Therapy Present & Future
Walters, Ethical Issues in Gene Therapy
Files on NPR, Internet
Course for Biology Teachers
at Proteins to Understand Expression
for Protein Analysis
100 Award Goes to LANL's SOLVE
Awards Proteomics Grant to Axys
coli Proteome Database
Genetics in Medicine
Organization for Rare Disorders
of Genetics to Medicine: New Website
Genetics Web Site
Website Offers Education in New Genetics
of Genetic Risks 2nd Edition
Research Genomics Online
Database Operations Restored
Silico Biology: Bioinformatics Journal
Methods Book Available
Programs at Sanger
Licenses Gene Logic Software
Database at LANL
at Jackson Laboratory
Database on Web
Web, Other Resources, Publications
Oakland Workshop Website
to Human Chromosomes
Office of Science Grants and Contracts
National Service Award Fellowships
Technologies for Molecular Analysis
Netork for Large-Scale Mouse Sequencing
Genomic Technology Development
Genome Research Funding
Meeting Calendars & Acronyms
and Biotechnology Meetings
Courses and Workshops
Microbial Genomics News
The National Center for Biotechnology Information (NCBI) Web site links to sequences from unfinished microbial genomes for BLAST searching. These unfinished sequences, which are not yet in GenBank nor accessible via Entrez, also can be retrieved from their associated sequencing centers by ftp or Web. The 18 finished microbial genomes are searchable by Entrez via the NCBI site.
In September 1998, The Institute for Genomic Research (TIGR) announced the release of more than 1.9 Mb of genome sequence from Chlorobium tepidum, a photosynthetic gram-negative bacterium. The TIGR program, supported by DOE, has reached 3 coverage in the random-sequencing phase. The photosynthetic C. tepidum may play an important role in the earth's overall cycle of carbon use.
Microbial-Genomes is a newsgroup for the discussion of microbial (bacterial, archaeal, and small eukaryotic) genomes. To subscribe, send the command subscribe microbial-genomes as the only text in the body of a message.
The May-June 1998 issue of ScienceWatch, a publication of the Philadelphia-based Institute for Scientific Information, noted that the paper describing the complete genomic sequence of the 1.7-Mb archaeon Methanococcus jannaschii was the fifth most-cited paper in biology for the first 2 months of 1998. The paper, by C.J. Bult and others at The Institute for Genomic Research, confirmed the existence of a third kingdom of life on earth when it appeared in 1996 in Science (273, 1058). At the time of publication, only about one-third of the 1700 genes in M. jannaschii were found to resemble known genes, and the other two-thirds were completely novel to biology. This research was supported by the DOE Microbial Genome Program.
The Genome Information Broker (GIB) now includes 18 microbial genomes that have been sequenced completely and released from DDBJ, EMBL, and GenBank databases. GIB information includes the numbers and names of clones, open reading frames and genes, and sequences. Results are represented in interactive graphics and tables.
Web sites at the University of Illinois at Urbana-Champaign present
- Sequenced and incomplete genomes, including microbial, found in public databases, with links to sequencing institution, functional overview, publication, and further information.
- Continuous annotations of Methanococcus jannaschii functions
The electronic form of the newsletter may be cited in the following style:
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Human Genome Program, U.S. Department of Energy, Human Genome News (v10n1-2).