In this issue...
HGP on Fast Track
Joint Genome Institute Exceeds Goal
Sequencing with BACs
with STCs and STSs
of BAC Clones and STC Data
Resource Success Story
Hunt SNPs for Variation, Disease
Sequencing the Human Genome?
Progress in Science
Promotes Remote Access to Instrumentation
Private-Sector Sequencing Project
In the News
Delivers C. elegans Sequence
Sequence Entire Genomes? Worm's Eye View
BER Research Update
1998 Human Genome Awards Announced
Consortium for Functional Genomics
Merges Offices, Web Sites
Microbial Genomes Searchable
Releases Chlorobium tepidum Sequence
MGP Abstracts Online
Ethical, Legal, and Social Issues
and Educational Resources
Lander, Genetics in the 21st Century
Rothstein, Genetic Privacy
Wilson, Gene Therapy Present & Future
Walters, Ethical Issues in Gene Therapy
Files on NPR, Internet
Course for Biology Teachers
at Proteins to Understand Expression
for Protein Analysis
100 Award Goes to LANL's SOLVE
Awards Proteomics Grant to Axys
coli Proteome Database
Genetics in Medicine
Organization for Rare Disorders
of Genetics to Medicine: New Website
Genetics Web Site
Website Offers Education in New Genetics
of Genetic Risks 2nd Edition
Research Genomics Online
Database Operations Restored
Silico Biology: Bioinformatics Journal
Methods Book Available
Programs at Sanger
Licenses Gene Logic Software
Database at LANL
at Jackson Laboratory
Database on Web
Web, Other Resources, Publications
Oakland Workshop Website
to Human Chromosomes
Office of Science Grants and Contracts
National Service Award Fellowships
Technologies for Molecular Analysis
Netork for Large-Scale Mouse Sequencing
Genomic Technology Development
Genome Research Funding
Meeting Calendars & Acronyms
and Biotechnology Meetings
Courses and Workshops
Software Programs Provide Useful Resources
BioToolKit now provides 750 annotated links to Web tools for the study of nucleic acid, genome, and protein structure.
Updated versions of gene-finding programs (including FGENES, FGENESH, and FGENES-m variant for mammalian sequences) are available for use through the Sanger Web site. Also, the Gapped BLASTP program from the National Center for Biotechnology Information allows users to check a gene's protein structure in the INFOGENEP database of finished and unfinished human sequences and receive the clone's name and sequence. See the Web site for more information.
The National Center for Biotechnology Information has released Version 2.80 of Sequin, the sequence-submission and editing tool, for all platforms. This version is expected to be particularly useful for genome centers that annotate large records.
Gary Benson (Mount Sinai School of Medicine) has developed a program to find tandem repeats in DNA sequence data without prior knowledge of pattern repeat, pattern size, or number of copies. The current version finds pattern repeats ranging from 1 to 500 bases.
Users submitting a sequence (up to 2 Mb) in FASTA format will receive a summary table of repeats, including their location, size, number of copies, and nucleotide content. Clicking on an entry shows alignment against a consensus pattern, allowing the user to see the repeat pattern and mutation location.
Sequence Viewer, a free public software tool for viewing and analyzing DNA sequences, is available on the National Center for Genome Resources (NCGR) Web site. The NCGR tool was developed to fill the need for graphical representations of nucleotide sequences in the Genome Sequence DataBase and for detailed descriptions of sequence annotation. Sequence Viewer allows users to quickly find a sequence region that integrates with a gene rather than searching through a lengthy, complex flat-file report. It also can be used as a quality-control tool for readily locating mistakes in feature position.
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Human Genome Program, U.S. Department of Energy, Human Genome News (v10n1-2).