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Media Contacts
![An organic solvent and water separate and form nanoclusters on the hydrophobic and hydrophilic sections of plant material, driving the efficient deconstruction of biomass. Credit: Michelle Lehman/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2020-11/dark_image_small.png?h=2e111cc1&itok=drKqW05b)
Experiments led by researchers at ORNL have determined that several hepatitis C drugs can inhibit the SARS-CoV-2 main protease, a crucial protein enzyme that enables the novel coronavirus to reproduce.
![coronavirus](/sites/default/files/styles/list_page_thumbnail/public/2020-11/coronavirus_top10%20%28002%29.png?h=997b30da&itok=7I6TjG_l)
NellOne Therapeutics has licensed a drug delivery system from the Department of Energy’s Oak Ridge National Laboratory that is designed to transport therapeutics directly to cells infected by SARS-CoV-2, the virus causing COVID-19.
![ORNL assisted in investigating proteins called porins, one shown in red, which are found in the protective outer membrane of certain disease-causing bacteria and tether the membrane to the cell wall. Credit: Hyea (Sunny) Hwang/Georgia Tech and ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2020-11/Biology-gram-negative_0.jpg?h=ced0ee1c&itok=mTOudglI)
Scientists from Oak Ridge National Laboratory used high-performance computing to create protein models that helped reveal how the outer membrane is tethered to the cell membrane in certain bacteria.
![Sandra Davern performs cell based assays to evaluate cell death and DNA damage in response to radiation in order to gain a better understanding of how radioisotope nanoparticles affect the human body.](/sites/default/files/styles/list_page_thumbnail/public/2020-10/2020-P15712.jpg?h=036a71b7&itok=6cpxN4v2)
When Sandra Davern looks to the future, she sees individualized isotopes sent into the body with a specific target: cancer cells.
![The first neutron structure of the SARS-CoV-2 main protease enzyme revealed unexpected electrical charges in the amino acids cysteine (negative) and histidine (positive), providing key data about the virus’s replication. Credit: Jill Hemman/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2020-10/20-G01620_Protease_PR_proof2_0.jpg?h=3e3883a3&itok=XB_ZEDFQ)
To better understand how the novel coronavirus behaves and how it can be stopped, scientists have completed a three-dimensional map that reveals the location of every atom in an enzyme molecule critical to SARS-CoV-2 reproduction.
A collaboration between the ORNL and a Florida-based medical device manufacturer has led to the addition of 500 jobs in the Miami area to support the mass production of N95 respirator masks.
![Emma Betters Thumbnail](/sites/default/files/styles/list_page_thumbnail/public/2020-10/emma%20betters_sized.jpg?h=e91a75a9&itok=k1X4xVjl)
Growing up in Florida, Emma Betters was fascinated by rockets and for good reason. Any time she wanted to see a space shuttle launch from NASA’s nearby Kennedy Space Center, all she had to do was sit on her front porch.
![Shown here is an on-chip carbonized electrode microstructure from a scanning electron microscope. Credit: ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2020-10/Lavrik%20Story%20Tip_0.jpg?h=33192216&itok=nNMwVUtU)
Scientists at Oak Ridge National Laboratory and the University of Tennessee designed and demonstrated a method to make carbon-based materials that can be used as electrodes compatible with a specific semiconductor circuitry.
![ORNL researchers and energy storage startup Sparkz have developed a cobalt-free cathode material for use in lithium-ion batteries Credit: Ilias Belharouak/Oak Ridge National Laboratory, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2020-10/cobalt-sparkz_0.jpg?h=cd715a88&itok=vTU2FKUY)
Four research teams from the Department of Energy’s Oak Ridge National Laboratory and their technologies have received 2020 R&D 100 Awards.
![ORNL Technical Assistance Program](/sites/default/files/styles/list_page_thumbnail/public/2020-09/ORNLTechAssistance1120x480_1.jpg?h=638bfecd&itok=2nAJF4Wb)
Experts at the Department of Energy’s Oak Ridge National Laboratory are now offering short-term technical and scientific assistance to entities working to combat the coronavirus through the COVID-19 Technical Assistance Program, an initiative of DOE’s Office of Technology Transitions.