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Media Contacts
![The AI agent, incorporating a language model-based molecular generator and a graph neural network-based molecular property predictor, processes a set of user-provided molecules (green) and produces/suggests new molecules (red) with desired chemical/physical properties (i.e. excitation energy). Image credit: Pilsun You, Jason Smith/ORNL, U.S. DOE](/sites/default/files/styles/list_page_thumbnail/public/2023-12/image001_0.png?h=16ec4b77&itok=KtCjteSq)
A team of computational scientists at ORNL has generated and released datasets of unprecedented scale that provide the ultraviolet visible spectral properties of over 10 million organic molecules.
![2023 Battelle Distinguished Inventors](/sites/default/files/styles/list_page_thumbnail/public/2023-11/23-G07641-Battelle-Distinguished-Inventor-graphic-pcg_0.jpg?h=d1cb525d&itok=uhmqAKgT)
Four scientists affiliated with ORNL were named Battelle Distinguished Inventors during the lab’s annual Innovation Awards on Dec. 1 in recognition of being granted 14 or more United States patents.
![Scientists conducted microbial DNA sampling at a Yellowstone National Park hot spring for a study sponsored by DOE’s Biological and Environmental Research program, the National Science Foundation and NASA. Credit: Mircea Podar/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2023-09/hot-springs_0.png?h=e68b456d&itok=ioNfSScN)
Oak Ridge National Laboratory scientists studied hot springs on different continents and found similarities in how some microbes adapted despite their geographic diversity.
![ORNL researchers, from left, Yang Liu, Xiaohan Yang and Torik Islam, collaborated on the development of a new capability to insert multiple genes simultaneously for fast, efficient transformation of plants into better bioenergy feedstocks. Credit: Genevieve Martin/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2023-06/Gene%20stacking%202023-P03111_0.jpg?h=c6980913&itok=RSUZXZ8U)
In a discovery aimed at accelerating the development of process-advantaged crops for jet biofuels, scientists at ORNL developed a capability to insert multiple genes into plants in a single step.
![ORNL scientists mutated amino acids in a receptor protein, shown in green, which diminished interaction with the SARS-CoV-2 virus spike protein, shown in red. Mutating the receptor protein hampered the virus’s ability to infect host cells. Credit: ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2023-04/Storytip-protein_0.png?h=c3a10d6e&itok=gUAu6nd8)
Oak Ridge National Laboratory scientists exploring bioenergy plant genetics have made a surprising discovery: a protein domain that could lead to new COVID-19 treatments.
![Oak Ridge National Laboratory led a team of scientists to design a molecule that disrupts the infection mechanism of the SARS-CoV-2 coronavirus and could be used to develop new treatments for COVID-19 and future virus outbreaks. Credit: Michelle Lehman/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2023-03/Picture1_0.png?h=d55ce37e&itok=Q2qLUWnE)
A team of scientists led by the Department of Energy’s Oak Ridge National Laboratory designed a molecule that disrupts the infection mechanism of the SARS-CoV-2 coronavirus and could be used to develop new treatments for COVID-19 and other viral diseases.
![ORNL’s biosensor system reveals CRISPR activity in poplar plants, which glow bright green under ultraviolet light, compared to normal plants, which appear red. Credit: Guoliang Yuan/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2021-12/GFPuv.png?h=b657ac0b&itok=Qs2Z_btM)
Detecting the activity of CRISPR gene editing tools in organisms with the naked eye and an ultraviolet flashlight is now possible using technology developed at ORNL.
![Carrie Eckert](/sites/default/files/styles/list_page_thumbnail/public/2021-11/2021-P08048.jpg?h=fdb72c6d&itok=pWcXR26-)
Carrie Eckert applies her skills as a synthetic biologist at ORNL to turn microorganisms into tiny factories that produce a variety of valuable fuels, chemicals and materials for the growing bioeconomy.
![ORNL metabolic engineer Adam Guss develops genetic tools to modify microbes that can perform a range of processes needed to create sustainable biofuels and bioproducts. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2021-08/2021-P05224.jpg?h=8f9cfe54&itok=_5e3ckBD)
As a metabolic engineer at Oak Ridge National Laboratory, Adam Guss modifies microbes to perform the diverse processes needed to make sustainable biofuels and bioproducts.
![ORNL’s Josh Michener, a microbiologist and metabolic engineer, led the discovery of a useful new enzyme that breaks down stubborn bonds in lignin, a polymer found in plants that typically becomes waste during bioconversion. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2021-06/2019-P05683_0.jpg?h=4c5cadcc&itok=FSVdbEYP)
In a step toward increasing the cost-effectiveness of renewable biofuels and bioproducts, scientists at ORNL discovered a microbial enzyme that degrades tough-to-break bonds in lignin, a waste product of biorefineries.