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Shown here is the structure of the NEMO protein. A team from ORNL conducted extensive molecular dynamics work on Summit by using both quantum mechanics and machine-learning methods to look at the binding affinity of NEMO and 3CLpro in humans and other species and to consider the structural models derived from the sequences of other coronaviruses. Image courtesy Nature Communications, Dan Jacobson/ORNL.

A new paper published in Nature Communications adds further evidence to the bradykinin storm theory of COVID-19’s viral pathogenesis — a theory that was posited two years ago by a team of researchers at the Department of Energy’s Oak Ridge National Laboratory.

Scott Stewart. Credit: Genevieve Martin/ORNL, U.S. Dept. of Energy

Though Scott Stewart recently received an Early Career Award from the Institute of Nuclear Material Management, he is regarded as a seasoned professional in the nuclear field with over 10 years of experience.

Solar panels funded by the Honnold Foundation are installed in Adjuntas, Puerto Rico. Credit: Fabio Andrade

When Hurricane Maria battered Puerto Rico in 2017, winds snapped trees and destroyed homes, while heavy rains transformed streets into rivers. But after the storm passed, the human toll continued to grow as residents struggled without electricity for months. Five years later, power outages remain long and frequent.

Biogeochemist Fernanda Santos works at a soil sampling site in Alaska as part of the ORNL-led NGEE–Arctic project. Credit: Amy Breen/University of Alaska Fairbanks

With wildfires increasing in scope and intensity around the world, Fernanda Santos’ research into how such calamities affect soil carbon storage has taken on new urgency.

ORNL fusion technology scientist Tim Bigelow, right, stands near the control console in ORNL’s  fusion control room with Matt Houde of Quaise Energy. Their partnership aims to tackle technical challenges with the Millimeter Wave Drilling System that Quaise has developed. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy.

Researchers in the geothermal energy industry are joining forces with fusion experts at ORNL to repurpose gyrotron technology, a tool used in fusion. Gyrotrons produce high-powered microwaves to heat up fusion plasmas.

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Global carbon emissions from inland waters such as lakes, rivers, streams and ponds are being undercounted by about 13% and will likely continue to rise given climate events and land use changes, ORNL scientists found.

ORNL researchers made a thermal insulation composite from hollow silica particles by mixing the particles with cellulose fibers. The composite proved to be highly moisture stable and shows potential for use in thermal applications. Credit: ORNL, U.S. Dept. of Energy

ORNL researchers demonstrated a process for producing a moisture-stable, lightweight thermal insulation material using hollow silica particles, or HSPs.

Researchers at Oak Ridge National Laboratory probed the chemistry of radium to gain key insights on advancing cancer treatments using radiation therapy. Credit: Adam Malin/ORNL, U.S. Dept. of Energy

Researchers at ORNL explored radium’s chemistry to advance cancer treatments using ionizing radiation.

Researchers used quantum Monte Carlo calculations to accurately render the structure and electronic properties of germanium selenide, a semiconducting nanomaterial. Credit: Paul Kent/ORNL, U.S. Dept. of Energy

A multi-lab research team led by ORNL's Paul Kent is developing a computer application called QMCPACK to enable precise and reliable predictions of the fundamental properties of materials critical in energy research.

A team of researchers used mathematics to predict which areas of the SARS-CoV-2 spike protein are most likely to mutate. Credit: Jill Hemman/ORNL, U.S. Dept. of Energy

Researchers from ORNL, the University of Tennessee at Chattanooga and Tuskegee University used mathematics to predict which areas of the SARS-CoV-2 spike protein are most likely to mutate.