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Computational biophysicist Ada Sedova is using experiments and high-performance computing to explore the properties of biological systems and predict their form and function, including research to accelerate drug discovery for COVID-19. Photo credit: Jason Richards, Oak Ridge National Laboratory, U.S. Dept. of Energy.

Ada Sedova’s journey to Oak Ridge National Laboratory has taken her on the path from pre-med studies in college to an accelerated graduate career in mathematics and biophysics and now to the intersection of computational science and biology

Using the single-crystal diffractometer TOPAZ, Oak Ridge National Laboratory confirmed the exact position of deuterium atoms from selective deuteration of benzene molecules. Credit: Oak Ridge National Laboratory, U.S. Dept. of Energy

Scientists have found a new method to strategically add deuterium to benzene, an aromatic compound commonly found in crude oil. When applied to the active ingredient of drugs to incorporate deuterium, it could dramatically improve the drugs’ efficacy and safety and even introduce new medicines.

Solid radium sulfate sits in the bottom of a flask during the recovery process. Credit: Oak Ridge National Laboratory, U.S. Dept. of Energy

Oak Ridge National Laboratory researchers have discovered a better way to separate actinium-227, a rare isotope essential for an FDA-approved cancer treatment.

Omar Demerdash

With the rise of the global pandemic, Omar Demerdash, a Liane B. Russell Distinguished Staff Fellow at ORNL since 2018, has become laser-focused on potential avenues to COVID-19 therapies.

Computing – Mining for COVID-19 connections

Scientists have tapped the immense power of the Summit supercomputer at Oak Ridge National Laboratory to comb through millions of medical journal articles to identify potential vaccines, drugs and effective measures that could suppress or stop the

Batteries - The 3D connection

Oak Ridge National Laboratory researchers have developed a thin film, highly conductive solid-state electrolyte made of a polymer and ceramic-based composite for lithium metal batteries.

Wireless charging – Special delivery for UPS

Researchers at Oak Ridge National Laboratory demonstrated a 20-kilowatt bi-directional wireless charging system on a UPS plug-in hybrid electric delivery truck, advancing the technology to a larger class of vehicles and enabling a new energy storage method for fleet owners and their facilities.

Materials — Molding molecular matter

Scientists at Oak Ridge National Laboratory used a focused beam of electrons to stitch platinum-silicon molecules into graphene, marking the first deliberate insertion of artificial molecules into a graphene host matrix.

Nuclear — Seeing inside particles

Oak Ridge National Laboratory researchers working on neutron imaging capabilities for nuclear materials have developed a process for seeing the inside of uranium particles – without cutting them open.

A new computational approach by ORNL can more quickly scan large-scale satellite images, such as these of Puerto Rico, for more accurate mapping of complex infrastructure like buildings. Credit: Maxar Technologies and Dalton Lunga/Oak Ridge National Laboratory, U.S. Dept. of Energy

A novel approach developed by scientists at ORNL can scan massive datasets of large-scale satellite images to more accurately map infrastructure – such as buildings and roads – in hours versus days.