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![coronavirus](/sites/default/files/styles/list_page_thumbnail/public/2020-11/coronavirus_top10%20%28002%29.png?h=997b30da&itok=7I6TjG_l)
NellOne Therapeutics has licensed a drug delivery system from the Department of Energy’s Oak Ridge National Laboratory that is designed to transport therapeutics directly to cells infected by SARS-CoV-2, the virus causing COVID-19.
![ORNL assisted in investigating proteins called porins, one shown in red, which are found in the protective outer membrane of certain disease-causing bacteria and tether the membrane to the cell wall. Credit: Hyea (Sunny) Hwang/Georgia Tech and ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2020-11/Biology-gram-negative_0.jpg?h=ced0ee1c&itok=mTOudglI)
Scientists from Oak Ridge National Laboratory used high-performance computing to create protein models that helped reveal how the outer membrane is tethered to the cell membrane in certain bacteria.
![Suman Debnath is using simulation algorithms to accelerate understanding of the modern power grid and enhance its reliability and resilience. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2021-01/Suman%20Debnath%20Square.jpg?h=439d043c&itok=1umME5uH)
Planning for a digitized, sustainable smart power grid is a challenge to which Suman Debnath is using not only his own applied mathematics expertise, but also the wider communal knowledge made possible by his revival of a local chapter of the IEEE professional society.
![Sandra Davern performs cell based assays to evaluate cell death and DNA damage in response to radiation in order to gain a better understanding of how radioisotope nanoparticles affect the human body.](/sites/default/files/styles/list_page_thumbnail/public/2020-10/2020-P15712.jpg?h=036a71b7&itok=6cpxN4v2)
When Sandra Davern looks to the future, she sees individualized isotopes sent into the body with a specific target: cancer cells.
![The first neutron structure of the SARS-CoV-2 main protease enzyme revealed unexpected electrical charges in the amino acids cysteine (negative) and histidine (positive), providing key data about the virus’s replication. Credit: Jill Hemman/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2020-10/20-G01620_Protease_PR_proof2_0.jpg?h=3e3883a3&itok=XB_ZEDFQ)
To better understand how the novel coronavirus behaves and how it can be stopped, scientists have completed a three-dimensional map that reveals the location of every atom in an enzyme molecule critical to SARS-CoV-2 reproduction.
![Scientists synthesized graphene nanoribbons (yellow) on a titanium dioxide substrate (blue). The lighter ends show magnetic states. Inset: The ends have up and down spin, ideal for creating qubits. Credit: ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2020-10/STM_Science_image_0.jpg?h=83401e72&itok=3oR6W30s)
An international multi-institution team of scientists has synthesized graphene nanoribbons – ultrathin strips of carbon atoms – on a titanium dioxide surface using an atomically precise method that removes a barrier for custom-designed carbon
![Water from local creeks now flows through these simulated streams in the Aquatic Ecology Laboratory, providing new opportunities to study mercury pollution and advance solutions. Credit: ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2020-10/img_3692.jpg?h=77bd3ecb&itok=dM1eszup)
New capabilities and equipment recently installed at the Department of Energy’s Oak Ridge National Laboratory are bringing a creek right into the lab to advance understanding of mercury pollution and accelerate solutions.
![These fuel assembly brackets, manufactured by ORNL in partnership with Framatome and Tennessee Valley Authority, are the first 3D-printed safety-related components to be inserted into a nuclear power plant. Credit: Fred List/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2020-10/FramatomeCB1.jpg?h=7c790887&itok=oVGkqZYZ)
The Transformational Challenge Reactor, or TCR, a microreactor built using 3D printing and other new advanced technologies, could be operational by 2024.
![stacked poplar logs](/sites/default/files/styles/list_page_thumbnail/public/2020-10/poplar_sized.jpg?h=e91a75a9&itok=Oq847ULr)
Popular wisdom holds tall, fast-growing trees are best for biomass, but new research by two U.S. Department of Energy national laboratories reveals that is only part of the equation.
![An ORNL researcher holds a capsule of molten salt. Preliminary experiments seem to indicate that irradiation can slow corrosion of metal in liquid salt. Credit: ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2020-10/salt_irr_01_0.jpg?h=b69e0e0e&itok=cwf13UxX)
Irradiation may slow corrosion of alloys in molten salt, a team of Oak Ridge National Laboratory scientists has found in preliminary tests.