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Alex Roschli in front of BAAM

Alex Roschli is no stranger to finding himself in unique situations. After all, the early career researcher in ORNL’s Manufacturing Systems Research group bears a last name that only 29 other people share in the United States, and he’s certain he’s the only Roschli (a moniker that hails from Switzerland) with the first name Alex.

Illustration of the intricate organization of the PKA structure, wherein different parts of the protein are connected through elaborate hydrogen bonding networks (dashed yellow lines), glued together by the hydrophobic assemblies (light blue and orange volumes)—all working together to build the functional active site. Insert shows protonation of the transferred phosphoryl group (cyan mesh) and its many interactions with water and the active site amino acid residues. Credit: Jill Hemman/ORNL

OAK RIDGE, Tenn., March 20, 2019—Direct observations of the structure and catalytic mechanism of a prototypical kinase enzyme—protein kinase A or PKA—will provide researchers and drug developers with significantly enhanced abilities to understand and treat fatal diseases and neurological disorders such as cancer, diabetes, and cystic fibrosis.

The concrete parts are installed in a residential and commercial tower (above center and below) on the site of the Domino Sugar Factory along the waterfront in Brooklyn. Windows in the tower resemble sugar crystals. Image credit: Gate Precast

A residential and commercial tower under development in Brooklyn that is changing the New York City skyline has its roots in research at the Department of Energy’s Oak Ridge National Laboratory.

Neutron scattering allowed direct observation of how aurein induces lateral segregation in the bacteria membranes, which creates instability in the membrane structure. This instability causes the membranes to fail, making harmful bacteria less effective.

As the rise of antibiotic-resistant bacteria known as superbugs threatens public health, Oak Ridge National Laboratory’s Shuo Qian and Veerendra Sharma from the Bhaba Atomic Research Centre in India are using neutron scattering to study how an antibacterial peptide interacts with and fights harmful bacteria.

Trees in an Oak Ridge National Laboratory plot

Higher carbon dioxide levels caused 30 percent more wood growth in young forest stands across the temperate United States over a decade, according to an analysis led by Oak Ridge National Laboratory.

ORNL will use state-of-the-art R&D tools at the Battery Manufacturing Facility to develop new methods for separating and reclaiming valuable materials from spent EV batteries.

The use of lithium-ion batteries has surged in recent years, starting with electronics and expanding into many applications, including the growing electric and hybrid vehicle industry. But the technologies to optimize recycling of these batteries have not kept pace.

Using neutrons from the TOPAZ beamline, which is optimal for locating hydrogen atoms in materials, ORNL researchers observed a single-crystal neutron diffraction structure of the insoluble carbonate salt formed by absorption of carbon dioxide from the air.

Researchers used neutron scattering at Oak Ridge National Laboratory’s Spallation Neutron Source to investigate the effectiveness of a novel crystallization method to capture carbon dioxide directly from the air.

Laminations such as these are compiled to form the core of modern electric vehicle motors. ORNL has developed a software toolkit to speed the development of new motor designs and to improve the accuracy of their real-world performance.

Oak Ridge National Laboratory scientists have created open source software that scales up analysis of motor designs to run on the fastest computers available, including those accessible to outside users at the Oak Ridge Leadership Computing Facility.

Researchers used machine learning methods on the ORNL Compute and Data Environment for Science, or CADES, to map vegetation communities in the Kougarok Watershed on the Seward Peninsula of Alaska. The colors denote different types of vegetation, such as w

A team of scientists led by Oak Ridge National Laboratory used machine learning methods to generate a high-resolution map of vegetation growing in the remote reaches of the Alaskan tundra.