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Alex Johs at ORNL's Spallation Neutron Source

Sometimes solutions to the biggest problems can be found in the smallest details. The work of biochemist Alex Johs at Oak Ridge National Laboratory bears this out, as he focuses on understanding protein structures and molecular interactions to resolve complex global problems like the spread of mercury pollution in waterways and the food supply.

Researchers from NIST and the University of Maryland standing in front of the Bio-SANS equipment.

Scientists from the National Institute of Standards and Technology (NIST) and the University of Maryland are using neutrons at Oak Ridge National Laboratory (ORNL) to capture new information about DNA and RNA molecules and enable more accurate computer simulations of how they interact with everything from proteins to viruses.

Neutrons—Mastering magnetism

Researchers have pioneered a new technique using pressure to manipulate magnetism in thin film materials used to enhance performance in electronic devices.

Quantum—Squeezed light cuts noise

Oak Ridge National Laboratory physicists studying quantum sensing, which could impact a wide range of potential applications from airport security scanning to gravitational wave measurements, have outlined in ACS Photonics the dramatic advances in the field.

Computing—Routing out the bugs

A study led by Oak Ridge National Laboratory explored the interface between the Department of Veterans Affairs’ healthcare data system and the data itself to detect the likelihood of errors and designed an auto-surveillance tool

Materials—Engineering heat transport

Scientists have discovered a way to alter heat transport in thermoelectric materials, a finding that may ultimately improve energy efficiency as the materials

Samples of 70% dark chocolate prepared for study with the USANS instrument at the Spallation Neutron Source. (Credit: ORNL/Genevieve Martin)

Tempering, the heating process that gives chocolate its appealing sheen and creamy texture, is a crucial part of crafting quality chocolate. But, at the molecular level, it gets a little tricky, and when done incorrectly, can render entire batches of chocolate gritty and unappetizing.

The researchers used the new model to accurately identify clusters of gene mutations (spheres), which helped them study the emergence of various genetic diseases. Image credit: Ivaylo Ivanov, Georgia State University.

Environmental conditions, lifestyle choices, chemical exposure, and foodborne and airborne pathogens are among the external factors that can cause disease. In contrast, internal genetic factors can be responsible for the onset and progression of diseases ranging from degenerative neurological disorders to some cancers.

Illustration of a tooth cross-section showing a dental filling adhered with adhesive resin containing nanoparticles. The resin layer is highlighted in yellow, with labels indicating its bioactive function (preventing cracks by forming crystals in micro-gaps) and antibacterial function (killing bacteria on contact, enhanced by visible light). The surrounding gum tissue and biofilm are also depicted, emphasizing the protective properties of the adhesive.

To help address the issue of dental restoration, Oak Ridge National Laboratory researchers are using neutron scattering to study how nanoparticles with antibacterial properties can be added to adhesive resins, which are used by dentists to strengthen the bond between a tooth and its polymer composite filling.

Virtual universes

Using Summit, the world’s most powerful supercomputer housed at Oak Ridge National Laboratory, a team led by Argonne National Laboratory ran three of the largest cosmological simulations known to date.