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![Analyses of lung fluid cells from COVID-19 patients conducted on the nation’s fastest supercomputer point to gene expression patterns that may explain the runaway symptoms produced by the body’s response to SARS-CoV-2. Credit: Jason B. Smith/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2020-07/cells%20200%5B1%5D.png?h=b95f6d72&itok=V2OxqL5l)
A team led by Dan Jacobson of Oak Ridge National Laboratory used the Summit supercomputer at ORNL to analyze genes from cells in the lung fluid of nine COVID-19 patients compared with 40 control patients.
![Omar Demerdash](/sites/default/files/styles/list_page_thumbnail/public/2020-05/demerdash_crop.jpg?h=8831409f&itok=2J2gUqDr)
With the rise of the global pandemic, Omar Demerdash, a Liane B. Russell Distinguished Staff Fellow at ORNL since 2018, has become laser-focused on potential avenues to COVID-19 therapies.
![GIS – LandScan goes public](/sites/default/files/styles/list_page_thumbnail/public/2020-05/sanfran%20%281%29_2.png?h=ea18fbc4&itok=c_VbFqAC)
Oak Ridge National Laboratory’s high-resolution population distribution database, LandScan USA, became permanently available to researchers in time to aid the response to the novel coronavirus pandemic.
![Coronavirus research](/sites/default/files/styles/list_page_thumbnail/public/2020-03/still_original.png?h=d1cb525d&itok=0Md1n6Ct)
Researchers at the Department of Energy’s Oak Ridge National Laboratory have used Summit, the world’s most powerful and smartest supercomputer, to identify 77 small-molecule drug compounds that might warrant further study in the fight
![A new computational approach by ORNL can more quickly scan large-scale satellite images, such as these of Puerto Rico, for more accurate mapping of complex infrastructure like buildings. Credit: Maxar Technologies and Dalton Lunga/Oak Ridge National Laboratory, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2020-02/Puerto_Rico_Resflow9.png?h=a0a1befd&itok=5n2fss_e)
A novel approach developed by scientists at ORNL can scan massive datasets of large-scale satellite images to more accurately map infrastructure – such as buildings and roads – in hours versus days.
![Dalton Lunga](/sites/default/files/styles/list_page_thumbnail/public/2020-01/Dalton_Lunga.jpg?h=4dcbbf6e&itok=0FQ-t5EF)
A typhoon strikes an island in the Pacific Ocean, downing power lines and cell towers. An earthquake hits a remote mountainous region, destroying structures and leaving no communication infrastructure behind.
![Smart Neighborhood homes](/sites/default/files/styles/list_page_thumbnail/public/2020-01/04.09.TD-SMartHome_0.jpg?h=5b5a5437&itok=22S5Tle1)
To better determine the potential energy cost savings among connected homes, researchers at Oak Ridge National Laboratory developed a computer simulation to more accurately compare energy use on similar weather days.