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Media Contacts
![The protease protein is both shaped like a heart and functions as one, allowing the virus replicate and spread. Inhibiting the protease would block virus reproduction. Credit: Andrey Kovalevsky/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2020-06/protease_dimer_3_1.png?h=aa51a450&itok=sJY7AB8d)
A team of researchers has performed the first room-temperature X-ray measurements on the SARS-CoV-2 main protease — the enzyme that enables the virus to reproduce.
![At the U.S. Department of Energy Manufacturing Demonstration Facility at ORNL, this part for a scaled-down prototype of a reactor was produced for industry partner Kairos Power.](/sites/default/files/styles/list_page_thumbnail/public/2020-05/Kairos%20PI%201_0.jpg?h=71976bb4&itok=EYVPB9H3)
Scientists at the Department of Energy Manufacturing Demonstration Facility at ORNL have their eyes on the prize: the Transformational Challenge Reactor, or TCR, a microreactor built using 3D printing and other new approaches that will be up and running by 2023.
![Omar Demerdash](/sites/default/files/styles/list_page_thumbnail/public/2020-05/demerdash_crop.jpg?h=8831409f&itok=2J2gUqDr)
With the rise of the global pandemic, Omar Demerdash, a Liane B. Russell Distinguished Staff Fellow at ORNL since 2018, has become laser-focused on potential avenues to COVID-19 therapies.
![Transformational Challenge Reactor Demonstration items](/sites/default/files/styles/list_page_thumbnail/public/2020-03/Press_release_image.jpg?h=b707efd5&itok=-Sxbmt8D)
Researchers at the Department of Energy’s Oak Ridge National Laboratory are refining their design of a 3D-printed nuclear reactor core, scaling up the additive manufacturing process necessary to build it, and developing methods
![Simulations forecast nationwide increase in human exposure to extreme climate events](/sites/default/files/styles/list_page_thumbnail/public/2020-05/us_population_exposure_0.jpg?h=854a7be2&itok=sagvawwJ)
OAK RIDGE, Tenn., May 5, 2020 — By 2050, the United States will likely be exposed to a larger number of extreme climate events, including more frequent heat waves, longer droughts and more intense floods, which can lead to greater risks for human health, ecosystem stability and regional economies.
![Ecosystem Ecologist Verity Salmon captures and analyzes field data from sites in in Alaska and Minnesota to inform earth system models that are being used to predict environmental change.](/sites/default/files/styles/list_page_thumbnail/public/2020-04/Salmon_CreditColleenIversen_0.jpg?h=6eb229a4&itok=cjwhvth8)
While some of her earth system modeling colleagues at ORNL face challenges such as processor allocation or debugging code, Verity Salmon prepares for mosquito swarms and the possibility of grizzly bears.
![Coronavirus graphic](/sites/default/files/styles/list_page_thumbnail/public/2020-04/covid19_jh_0.png?h=d1cb525d&itok=PyngFUZw)
In the race to identify solutions to the COVID-19 pandemic, researchers at the Department of Energy’s Oak Ridge National Laboratory are joining the fight by applying expertise in computational science, advanced manufacturing, data science and neutron science.
![Researchers discovered the Tennessee cavesnail, Antrorbis tennesseensis, in caves near Oak Ridge National Laboratory. The snail measures in at less than 2 millimeters long. Credit: Nathaniel Shoobs and Matthew Niemiller](/sites/default/files/styles/list_page_thumbnail/public/2020-04/Cave_snailREV.jpg?h=c96bab7a&itok=6rjc3NQL)
Sometimes conducting big science means discovering a species not much larger than a grain of sand.
![VERA’s tools allow a virtual “window” inside the reactor core, down to a molecular level.](/sites/default/files/styles/list_page_thumbnail/public/2020-03/core.png?h=dc920c3f&itok=BggaFrQA)
A software package, 10 years in the making, that can predict the behavior of nuclear reactors’ cores with stunning accuracy has been licensed commercially for the first time.
![Coronavirus research](/sites/default/files/styles/list_page_thumbnail/public/2020-03/still_original.png?h=d1cb525d&itok=0Md1n6Ct)
Researchers at the Department of Energy’s Oak Ridge National Laboratory have used Summit, the world’s most powerful and smartest supercomputer, to identify 77 small-molecule drug compounds that might warrant further study in the fight