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Rich Giannone uses bioanalytical mass spectrometry to examine proteins, the primary driver in biological systems.

Rich Giannone uses bioanalytical mass spectrometry to examine proteins, the primary driver in biological systems.

ORNL researchers used electron beam powder bed fusion to produce refractory metal molybdenum, which remained crack free and dense, proving its viability for additive manufacturing applications. Credit: ORNL/U.S. Dept. of Energy

Oak Ridge National Laboratory scientists proved molybdenum titanium carbide, a refractory metal alloy that can withstand extreme temperature environments, can also be crack free and dense when produced with electron beam powder bed fusion. 

An ORNL-invented electrocatalyst made of custom-designed alloy nanoparticles embedded in carbon nanospikes was licensed by Prometheus Fuels and further developed to aid a process to convert solar and wind electricity into chemical energy for electrofuels. Credit: ORNL, U.S. Dept. of Energy

In a new twist to an existing award-winning ORNL technology, researchers have developed an electrocatalyst that enables water and carbon dioxide to be split and the atoms recombined to form higher weight hydrocarbons for gasoline, diesel and jet fuel.

ORNL researchers used fiber reinforcements made of steel, glass and carbon to develop a concrete mix that demonstrated high early strength within six hours of production, which is needed for the precast concrete industry. Credit: ORNL/U.S. Dept. of Energy

A team of researchers at Oak Ridge National Laboratory and the University of Tennessee have developed a concrete mix that demonstrated high early strength within six hours of mixing, potentially doubling the production capacity for the precast industry.

ATOM logo

The Accelerating Therapeutics for Opportunities in Medicine , or ATOM, consortium today announced the U.S. Department of Energy’s Oak Ridge, Argonne and Brookhaven national laboratories are joining the consortium to further develop ATOM’s artificial intelligence, or AI-driven, drug discovery platform.

Targeted alpha therapy can deliver radiation to specific cells, with minimal effect on surrounding, healthy cells. Credit: Michelle Lehman and Jaimee Janiga/ORNL, U.S. Dept. of Energy

A rare isotope in high demand for treating cancer is now more available to pharmaceutical companies developing and testing new drugs.

Neutron scattering experiments show electric charges, shown in red, blue and grey, in the SARS-CoV-2 main protease site where telaprevir binds to the structure. The experiments provide critical data for the design of small-molecule drugs to treat COVID-19. Credit: Jill Hemman and Michelle Lehman/ORNL, U.S. Dept. of Energy

Scientists have found new, unexpected behaviors when SARS-CoV-2 – the virus that causes COVID-19 – encounters drugs known as inhibitors, which bind to certain components of the virus and block its ability to reproduce.  

ORNL researchers used gas metal arc welding additive technology to print the die for a B-pillar or vertical roof support structure for a sport utility vehicle, demonstrating a 20% improvement in the cooling rate. Credit: ORNL/U.S. Dept. of Energy

A team of Oak Ridge National Laboratory researchers demonstrated that an additively manufactured hot stamping die – a tool used to create car body components – cooled faster than those produced by conventional manufacturing methods.

Verónica Melesse Vergara speaks with third and fourth graders at East Side Intermediate School in Brownsville. Credit: ORNL, U.S. Dept. of Energy

Twenty-seven ORNL researchers Zoomed into 11 middle schools across Tennessee during the annual Engineers Week in February. East Tennessee schools throughout Oak Ridge and Roane, Sevier, Blount and Loudon counties participated, with three West Tennessee schools joining in.

ORNL has modeled the spike protein that binds the novel coronavirus to a human cell for better understanding of the dynamics of COVID-19. Credit: Stephan Irle/ORNL, U.S. Dept. of Energy

To better understand the spread of SARS-CoV-2, the virus that causes COVID-19, Oak Ridge National Laboratory researchers have harnessed the power of supercomputers to accurately model the spike protein that binds the novel coronavirus to a human cell receptor.