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The Accelerating Therapeutics for Opportunities in Medicine , or ATOM, consortium today announced the U.S. Department of Energy’s Oak Ridge, Argonne and Brookhaven national laboratories are joining the consortium to further develop ATOM’s artificial intelligence, or AI-driven, drug discovery platform.

Targeted alpha therapy can deliver radiation to specific cells, with minimal effect on surrounding, healthy cells. Credit: Michelle Lehman and Jaimee Janiga/ORNL, U.S. Dept. of Energy

A rare isotope in high demand for treating cancer is now more available to pharmaceutical companies developing and testing new drugs.

Data from the ORNL Free Air CO2 Enrichment experiment were combined with observations from more than 100 other FACE sites for this analysis, which revealed new insights about the relationship between plant biomass growth and soil carbon storage. Credit: Jeff Warren/ORNL, U.S. Dept. of Energy

Oak Ridge National Laboratory was among an international team, led by Lawrence Livermore National Laboratory, who synthesized 108 elevated carbon dioxide, or CO2, experiments performed in various ecosystems to find out how much carbon is

Neutron scattering experiments show electric charges, shown in red, blue and grey, in the SARS-CoV-2 main protease site where telaprevir binds to the structure. The experiments provide critical data for the design of small-molecule drugs to treat COVID-19. Credit: Jill Hemman and Michelle Lehman/ORNL, U.S. Dept. of Energy

Scientists have found new, unexpected behaviors when SARS-CoV-2 – the virus that causes COVID-19 – encounters drugs known as inhibitors, which bind to certain components of the virus and block its ability to reproduce.  

Nesaraja split her effort between nuclear data evaluation and experimentation at ORNL’s now-closed Holifield Radioactive Ion Beam Facility. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

Nuclear physicist Caroline Nesaraja of the Department of Energy’s Oak Ridge National Laboratory evaluates nuclear data vital to applied and basic sciences. 

Urban climate modeling

Researchers at Oak Ridge National Laboratory have identified a statistical relationship between the growth of cities and the spread of paved surfaces like roads and sidewalks. These impervious surfaces impede the flow of water into the ground, affecting the water cycle and, by extension, the climate.

ORNL researchers used an electrochemical process to heal dendrites that formed in a ceramic, garnet-based catalyst designed for a solid-state lithium battery. Credit: Andy Sproles/ORNL, U.S. Dept. of Energy

Scientists at Oak Ridge National Laboratory successfully demonstrated a technique to heal dendrites that formed in a solid electrolyte, resolving an issue that can hamper the performance of high energy-density, solid-state batteries.

Technicians John Dyer and T. Dyer use a manipulator arm in a shielded cave in ORNL’s Radiochemical Engineering Development Center to separate concentrated Pm-147 from byproducts generated through the production of Pu-238.

A new method developed at Oak Ridge National Laboratory proves one effort’s trash is another’s valuable isotope. One of the byproducts of the lab’s national plutonium-238 production program is promethium-147, a rare isotope used in nuclear batteries and to measure the thickness of materials.

Xin Sun

Xin Sun has been selected as the associate laboratory director for the Energy Science and Technology Directorate, or ESTD, at the Department of Energy’s Oak Ridge National Laboratory.

ORNL researchers are developing a method to print low-cost, high-fidelity, customizable sensors for monitoring power grid equipment. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

A method developed at Oak Ridge National Laboratory to print high-fidelity, passive sensors for energy applications can reduce the cost of monitoring critical power grid assets.