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ORNL’s Tomás Rush explores the secret lives of fungi and plants for insights into the interactions that determine plant health. Credit: Genevieve Martin/ORNL, U.S. Dept. of Energy

Tomás Rush began studying the mysteries of fungi in fifth grade and spent his college intern days tromping through forests, swamps and agricultural lands searching for signs of fungal plant pathogens causing disease on host plants.

Researchers at Oak Ridge National Laboratory probed the chemistry of radium to gain key insights on advancing cancer treatments using radiation therapy. Credit: Adam Malin/ORNL, U.S. Dept. of Energy

Researchers at ORNL explored radium’s chemistry to advance cancer treatments using ionizing radiation.

ORNL physicist Libby Johnson demonstrated a new control panel at ORNL’s Bulk Shielding Facility in 1957. Among the first females to operate a nuclear reactor, Johnson blazed trails for women. Credit: ORNL, U.S. Dept. of Energy

Oak Ridge National Laboratory physicist Elizabeth “Libby” Johnson (1921-1996), one of the world’s first nuclear reactor operators, standardized the field of criticality safety with peers from ORNL and Los Alamos National Laboratory.

Oak Ridge National Laboratory’s Mitch Allmond works with the Facility for Rare Isotope Beams Decay Station initiator, which combined diverse detectors for FRIB’s first experiment. Credit: Robert Grzywacz/ORNL, U.S. Dept. of Energy

Two decades in the making, a new flagship facility for nuclear physics opened on May 2, and scientists from the Department of Energy’s Oak Ridge National Laboratory have a hand in 10 of its first 34 experiments.

Physicist Charles Havener uses the NASA end station at ORNL’s Multicharged Ion Research Facility to simulate the origin of X-ray emissions from space. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

Scientists are using Oak Ridge National Laboratory’s Multicharged Ion Research Facility to simulate the cosmic origin of X-ray emissions resulting when highly charged ions collide with neutral atoms and molecules, such as helium and gaseous hydrogen.

ORNL, VA and Harvard researchers developed a sparse matrix full of anonymized information on what is thought to be the largest cohort of healthcare data used for this type of research in the U.S. The matrix can be probed with different methods, such as KESER, to gain new insights into human health. Credit: Nathan Armistead/ORNL, U.S. Dept. of Energy

A team of researchers has developed a novel, machine learning–based  technique to explore and identify relationships among medical concepts using electronic health record data across multiple healthcare providers.

Genetic analysis revealed connections between inflammatory activity and development of atomic dermatitis, according to researchers from the UPenn School of Medicine, the Perelman School of Medicine, and Oak Ridge National Laboratory. Credit: Kang Ko/UPenn

University of Pennsylvania researchers called on computational systems biology expertise at Oak Ridge National Laboratory to analyze large datasets of single-cell RNA sequencing from skin samples afflicted with atopic dermatitis.

An ORNL-led team studied the SARS-CoV-2 spike protein in the trimer state, shown here, to pinpoint structural transitions that could be disrupted to destabilize the protein and negate its harmful effects. Credit: Debsindhu Bhowmik/ORNL, U.S. Dept. of Energy

To explore the inner workings of severe acute respiratory syndrome coronavirus 2, or SARS-CoV-2, researchers from ORNL developed a novel technique.