Skip to main content
Neutron experiments helped reveal the one-carbon enzymatic mechanism that synthesizes vital food sources for cancer cells that depend on vitamin B6, providing key insights into designing novel drugs to slow the spread of aggressive cancers. Credit: Jill Hemman/ORNL, U.S. Dept. of Energy

After a highly lauded research campaign that successfully redesigned a hepatitis C drug into one of the leading drug treatments for COVID-19, scientists at ORNL are now turning their drug design approach toward cancer. 

Upgrades to the particle accelerator enabling the record 1.7-megawatt beam power at the Spallation Neutron Source included adding 28 high-power radio-frequency klystrons (red tubes) to provide higher power for the accelerator. Credit: Genevieve Martin/ORNL, U.S. Dept. of Energy

The Spallation Neutron Source at the Department of Energy's Oak Ridge National Laboratory set a world record when its particle accelerator beam operating power reached 1.7 megawatts, substantially improving on the facility’s original design capability.

TIP graphic

Scientist-inventors from ORNL will present seven new technologies during the Technology Innovation Showcase on Friday, July 14, from 8 a.m.–4 p.m. at the Joint Institute for Computational Sciences on ORNL’s campus.

ytterbium

ORNL’s electromagnetic isotope separator, or EMIS, made history in 2018 when it produced 500 milligrams of the rare isotope ruthenium-96, unavailable anywhere else in the world. 

Neutron scattering experiments at the Spallation Neutron Source revealed how the dynamics between copper and oxygen make a special type of enzyme excel at breaking down biomass. Insights could lead to lowering the cost of biofuel production. Credit: Jill Hemman/ORNL, U.S. Dept. of Energy

Nonfood, plant-based biofuels have potential as a green alternative to fossil fuels, but the enzymes required for production are too inefficient and costly to produce. However, new research is shining a light on enzymes from fungi that could make biofuels economically viable.

ORNL researchers used diamonds to compress materials to 1.2 million times ambient pressure and software to remove signal interference and extract data on pressure-induced atomic structures. Credit: Jill Hemman/ORNL, U.S. Dept. of Energy

For decades, scientists sought a way to apply the outstanding analytical capabilities of neutrons to materials under pressures approaching those surrounding the Earth’s core.

Mickey Wade

Mickey Wade has been named associate laboratory director for the Fusion and Fission Energy and Science Directorate at the Department of Energy’s Oak Ridge National Laboratory, effective April 1.

The licensing and leadership team behind AMIGO. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

A technology developed at ORNL and used by the U.S. Naval Information Warfare Systems Command, or NAVWAR, to test the capabilities of commercial security tools has been licensed to cybersecurity firm Penguin Mustache to create its Evasive.ai platform. The company was founded by the technology’s creator, former ORNL scientist Jared M. Smith, and his business partner, entrepreneur Brandon Bruce.

Heat is typically carried through a material by vibrations known as phonons. In some crystals, however, different atomic motions — known as phasons — carry heat three times faster and farther. This illustration shows phasons made by rearranging atoms, shown by arrows. Credit: Jill Hemman/ORNL, U.S. Dept. of Energy

Warming a crystal of the mineral fresnoite, ORNL scientists discovered that excitations called phasons carried heat three times farther and faster than phonons, the excitations that usually carry heat through a material.

Even small movements of hydrogen, shown in yellow, were found to cause large energy shifts in the attached iron atoms, shown in silver, which could be of interest in creating novel chemical reactions. Credit: Jill Hemman/ORNL, U.S. Dept. of Energy

Researchers from Yale University and ORNL collaborated on neutron scattering experiments to study hydrogen atom locations and their effects on iron in a compound similar to those commonly used in industrial catalysts.