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ORNL’s Adam Guss began adapting the SAGE gene editing tool to modify microbes in graduate school. Today, SAGE is rapidly accelerating the design of custom microbes for a variety of applications. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

A wise tool for modifying microbes

A DNA editing tool adapted by Oak Ridge National Laboratory scientists makes engineering microbes for everything from bioenergy production to plastics recycling easier and faster.

Fungal geneticist Joanna Tannous is gaining a better understanding of the genetic processes behind fungal life to both combat plant disease and encourage beneficial processes like soil carbon storage. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

Joanna Tannous: Harnessing an unlikely climate challenge ally

Joanna Tannous has found the perfect organism to study to satisfy her deeply curious nature, her skills in biochemistry and genetics, and a drive to create solutions for a better world. The organism is a poorly understood life form that greatly influences its environment and is unique enough to deserve its own biological kingdom: fungi.

Oak Ridge National Laboratory’s Dave Weston works in a chamber at the DOE SPRUCE whole ecosystem experiment site in the peatlands of northern Minnesota. Credit: Kyle Pearson/ORNL, U.S. Dept. of Energy

Scientists find sex differences in mosses play key role in carbon storage

A quest to understand how Sphagnum mosses facilitate the storage of vast amounts of carbon in peatlands led scientists to a surprising discovery: the plants have sex-based differences that appear to impact the carbon-storing process.

Computational systems biologists at ORNL worked with the U.S. Department of Veterans Affairs and other institutions to identify 139 locations across the human genome tied to risk factors for varicose veins, marking a first step in the development of new treatments. Credit: Andy Sproles/ORNL, U.S. Dept. of Energy

Computational study finds genetic links, therapy targets for varicose veins

As part of a multi-institutional research project, scientists at ORNL leveraged their computational systems biology expertise and the largest, most diverse set of health data to date to explore the genetic basis of varicose veins.

The Center for Bioenergy Innovation at Oak Ridge National Laboratory has added three new members to its board of directors, from left: Deborah Crawford, vice chancellor for research at the University of Tennessee, Knoxville; Susan Hubbard, deputy for science and technology at ORNL; and Maureen McCann, director of the Biosciences Center at the National Renewable Energy Laboratory. Credit: UT Knoxville, ORNL and NREL.

Center for Bioenergy Innovation adds three new board members

The Department of Energy’s Center for Bioenergy Innovation, led by Oak Ridge National Laboratory, recently added three new members to its board of directors: Deborah Crawford of the University of Tennessee, Knoxville; Susan Hubbard of ORNL; and Maureen McCann of the National Renewable Energy Laboratory.

Merlin Theodore

ORNL’s Merlin Theodore appointed to National Science Board

Merlin Theodore is one of eight new board members announced by President Biden; she will join the 25-member board for a six-year term.

A team of ORNL researchers used neutron diffraction experiments to study the 3D-printed ACMZ alloy and observed a phenomenon called “load shuffling” that could inform the design of stronger, better-performing lightweight materials for vehicles. Credit: ORNL, U.S. Dept. of Energy

Scientists use neutrons to discover strengthening behavior in alloys

ORNL researchers have identified a mechanism in a 3D-printed alloy – termed “load shuffling” — that could enable the design of better-performing lightweight materials for vehicles.

Hybrid poplar trees such as these shown in an ORNL greenhouse were engineered with the REVEILLE1 gene to delay dormancy and produce more biomass. The research was led by the Center for Bioenergy Innovation at ORNL with the Joint Genome Institute, Brookhaven National Laboratory, the HudsonAlpha Institute for Biotechnology, the University of Connecticut and other partners. Credit: Genevieve Martin/ORNL, U.S. Dept. of Energy

Agave gene delays poplar dormancy

A team of scientists led by ORNL discovered the gene in agave that governs when the plant goes dormant and used it to create poplar trees that nearly doubled in size, increasing biomass yield for biofuels production

Erica Prates is using her skills as a computational systems biologist to link the smallest molecules to their impact on large ecosystems. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

Erica Prates: Bridging science across scales with computational biology

Erica Prates has found a way to help speed the pursuit of healthier ecosystems by linking the function of the smallest molecules to their effects on large-scale processes, leveraging a combination of science, math and computing.