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Neutron experiments helped reveal the one-carbon enzymatic mechanism that synthesizes vital food sources for cancer cells that depend on vitamin B6, providing key insights into designing novel drugs to slow the spread of aggressive cancers. Credit: Jill Hemman/ORNL, U.S. Dept. of Energy

After a highly lauded research campaign that successfully redesigned a hepatitis C drug into one of the leading drug treatments for COVID-19, scientists at ORNL are now turning their drug design approach toward cancer. 

Credit: NAIC Arecibo Observatory, a facility of the NSF; (INSET) Michelle Negron, National Science Foundation

For more than half a century, the 1,000-foot-diameter spherical reflector dish at the Arecibo Observatory in Puerto Rico was the largest radio telescope in the world. Completed in 1963, the dish was built in a natural sinkhole, with the telescope’s feed antenna suspended 500 feet above the dish on a 1.8-million-pound steel platform. Three concrete towers and more than 4 miles of steel cables supported the platform.

Entrepreneur-fellows in Innovation Crossroads will complete the Spark Cleantech Accelerator, a 12-week program offered by the Spark Innovation Center at the University of Tennessee Research Park. Credit: UT Research Park

Entrepreneur-fellows in Innovation Crossroads will complete the Spark Cleantech Accelerator, a 12-week program offered by the Spark Innovation Center at the UT Research Park.

The DuAlumin-3D research team developed a lightweight, aluminum alloy for additive manufacturing. Credit: Carlos Jones, ORNL/U.S. Dept. of Energy

Dean Pierce of ORNL and a research team led by ORNL’s Alex Plotkowski were honored by DOE’s Vehicle Technologies Office for development of novel high-performance alloys that can withstand extreme environments.

Innovation Crossroads cohort 7

Seven entrepreneurs will embark on a two-year fellowship as the seventh cohort of Innovation Crossroads kicks off this month at ORNL. Representing a range of transformative energy technologies, Cohort 7 is a diverse class of innovators with promising new companies.

Yarom Polsky studio portrait

Yarom Polsky, director of the Manufacturing Science Division, or MSD, at the Department of Energy’s Oak Ridge National Laboratory, has been elected a Fellow of the American Society of Mechanical Engineers, or ASME.

Upgrades to the particle accelerator enabling the record 1.7-megawatt beam power at the Spallation Neutron Source included adding 28 high-power radio-frequency klystrons (red tubes) to provide higher power for the accelerator. Credit: Genevieve Martin/ORNL, U.S. Dept. of Energy

The Spallation Neutron Source at the Department of Energy's Oak Ridge National Laboratory set a world record when its particle accelerator beam operating power reached 1.7 megawatts, substantially improving on the facility’s original design capability.

Aerial shot of ORNL's campus. Credit: Kase Clapp/ORNL, U.S. Dept. of Energy

Four firms doing business with the Department of Energy’s Oak Ridge National Laboratory received ORNL Small Business Awards during an awards ceremony on June 29.

Researchers at the Department of Energy’s Oak Ridge National Laboratory were the first to use neutron reflectometry to peer inside a working solid-state battery and monitor its electrochemistry.

Researchers at the Department of Energy’s Oak Ridge National Laboratory were the first to use neutron reflectometry to peer inside a working solid-state battery and monitor its electrochemistry.

Herwig shared the impacts of neutron science with Secretary of Energy Jennifer Granholm during a tour of SNS in November 2021. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

Ken Herwig's scientific drive crystallized in his youth when he solved a tough algebra word problem in his head while tossing newspapers from his bicycle. He said the joy he felt in that moment as a teenager fueled his determination to conquer mathematical mysteries. And he did.