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Neutron experiments helped reveal the one-carbon enzymatic mechanism that synthesizes vital food sources for cancer cells that depend on vitamin B6, providing key insights into designing novel drugs to slow the spread of aggressive cancers. Credit: Jill Hemman/ORNL, U.S. Dept. of Energy

After a highly lauded research campaign that successfully redesigned a hepatitis C drug into one of the leading drug treatments for COVID-19, scientists at ORNL are now turning their drug design approach toward cancer. 

Credit: NAIC Arecibo Observatory, a facility of the NSF; (INSET) Michelle Negron, National Science Foundation

For more than half a century, the 1,000-foot-diameter spherical reflector dish at the Arecibo Observatory in Puerto Rico was the largest radio telescope in the world. Completed in 1963, the dish was built in a natural sinkhole, with the telescope’s feed antenna suspended 500 feet above the dish on a 1.8-million-pound steel platform. Three concrete towers and more than 4 miles of steel cables supported the platform.

ORNL-developed software tools for identifying and quantifying energy efficiency will be demonstrated to participants during an Energy Bootcamp sponsored by DOE’s Industrial Efficiency and Decarbonization Office. Credit: ORNL, U.S. Dept. of Energy

ORNL researchers have developed a training camp to help manufacturing industries reduce energy-related carbon dioxide emissions and improve cost savings.

ORNL will collaborate with Fairbanks Morse Defense on decarbonization efforts to develop alternative fuel technologies for marine engines. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

ORNL, the Department of Energy’s largest multidisciplinary laboratory, and Fairbanks Morse Defense, a portfolio company of Arcline Investment Management, have entered into a Memorandum of Understanding to collaborate on the development and integration of alternative fuel technologies aimed at reducing the marine engine’s reliance on fossil fuels. 

Innovation Crossroads cohort 7

Seven entrepreneurs will embark on a two-year fellowship as the seventh cohort of Innovation Crossroads kicks off this month at ORNL. Representing a range of transformative energy technologies, Cohort 7 is a diverse class of innovators with promising new companies.

Yarom Polsky studio portrait

Yarom Polsky, director of the Manufacturing Science Division, or MSD, at the Department of Energy’s Oak Ridge National Laboratory, has been elected a Fellow of the American Society of Mechanical Engineers, or ASME.

Upgrades to the particle accelerator enabling the record 1.7-megawatt beam power at the Spallation Neutron Source included adding 28 high-power radio-frequency klystrons (red tubes) to provide higher power for the accelerator. Credit: Genevieve Martin/ORNL, U.S. Dept. of Energy

The Spallation Neutron Source at the Department of Energy's Oak Ridge National Laboratory set a world record when its particle accelerator beam operating power reached 1.7 megawatts, substantially improving on the facility’s original design capability.

Researchers at the Department of Energy’s Oak Ridge National Laboratory were the first to use neutron reflectometry to peer inside a working solid-state battery and monitor its electrochemistry.

Researchers at the Department of Energy’s Oak Ridge National Laboratory were the first to use neutron reflectometry to peer inside a working solid-state battery and monitor its electrochemistry.

 Illustration of a laser-based analytical method to accelerate understanding of critical plant and soil properties with the aim of co-optimizing bioenergy plant growth and soil carbon storage

Oak Ridge National Laboratory researchers recently demonstrated use of a laser-based analytical method to accelerate understanding of critical plant and soil properties that affect bioenergy plant growth and soil carbon storage.

Tristen Mullins. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

Tristen Mullins enjoys the hidden side of computers. As a signals processing engineer for ORNL, she tries to uncover information hidden in components used on the nation’s power grid — information that may be susceptible to cyberattacks.