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Promethium’s secrets exposed
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Computational systems biologists at ORNL worked with the U.S. Department of Veterans Affairs and other institutions to identify 139 locations across the human genome tied to risk factors for varicose veins, marking a first step in the development of new treatments. Credit: Andy Sproles/ORNL, U.S. Dept. of Energy

Computational study finds genetic links, therapy targets for varicose veins

As part of a multi-institutional research project, scientists at ORNL leveraged their computational systems biology expertise and the largest, most diverse set of health data to date to explore the genetic basis of varicose veins.

The Center for Bioenergy Innovation at Oak Ridge National Laboratory has added three new members to its board of directors, from left: Deborah Crawford, vice chancellor for research at the University of Tennessee, Knoxville; Susan Hubbard, deputy for science and technology at ORNL; and Maureen McCann, director of the Biosciences Center at the National Renewable Energy Laboratory. Credit: UT Knoxville, ORNL and NREL.

Center for Bioenergy Innovation adds three new board members

The Department of Energy’s Center for Bioenergy Innovation, led by Oak Ridge National Laboratory, recently added three new members to its board of directors: Deborah Crawford of the University of Tennessee, Knoxville; Susan Hubbard of ORNL; and Maureen McCann of the National Renewable Energy Laboratory.

Hybrid poplar trees such as these shown in an ORNL greenhouse were engineered with the REVEILLE1 gene to delay dormancy and produce more biomass. The research was led by the Center for Bioenergy Innovation at ORNL with the Joint Genome Institute, Brookhaven National Laboratory, the HudsonAlpha Institute for Biotechnology, the University of Connecticut and other partners. Credit: Genevieve Martin/ORNL, U.S. Dept. of Energy

Agave gene delays poplar dormancy

A team of scientists led by ORNL discovered the gene in agave that governs when the plant goes dormant and used it to create poplar trees that nearly doubled in size, increasing biomass yield for biofuels production

Erica Prates is using her skills as a computational systems biologist to link the smallest molecules to their impact on large ecosystems. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

Erica Prates: Bridging science across scales with computational biology

Erica Prates has found a way to help speed the pursuit of healthier ecosystems by linking the function of the smallest molecules to their effects on large-scale processes, leveraging a combination of science, math and computing.