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Media Contacts
![Oak Ridge National Laboratory led a team of scientists to design a molecule that disrupts the infection mechanism of the SARS-CoV-2 coronavirus and could be used to develop new treatments for COVID-19 and future virus outbreaks. Credit: Michelle Lehman/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2023-03/Picture1_0.png?h=d55ce37e&itok=Q2qLUWnE)
A team of scientists led by the Department of Energy’s Oak Ridge National Laboratory designed a molecule that disrupts the infection mechanism of the SARS-CoV-2 coronavirus and could be used to develop new treatments for COVID-19 and other viral diseases.
![One of the proteins identified through a new ORNL-developed approach could be key to communications between poplar trees and beneficial microbes that can help boost poplar trees’ growth, carbon storage and climate resilience. Credit: Andy Sproles/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2023-03/Kalluri%20story%20tip%20March%202023_0.png?h=0c488664&itok=qs9pgkW3)
ORNL researchers have identified specific proteins and amino acids that could control bioenergy plants’ ability to identify beneficial microbes that can enhance plant growth and storage of carbon in soils.
![The next generation of the Center for Bioenergy Innovation will pursue an accelerated feedstock-to-fuels approach for the efficient, economic production of sustainable jet fuel. Credit: ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2023-03/jetswitchgrass.png?h=37039f64&itok=UGACTvHE)
The Center for Bioenergy Innovation has been renewed by the Department of Energy as one of four bioenergy research centers across the nation to advance robust, economical production of plant-based fuels and chemicals.
![Samantha Peters co-designed and conducted experiments using ORNL’s high-performance mass spectrometry techniques to prove that bacteriophages deploy genetic code-switching to overwhelm and destroy host bacteria. Credit: Genevieve Martin, ORNL/U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2023-03/2023-P00717_0.jpg?h=2b2da530&itok=Ae7uW6ug)
Scientists at ORNL have confirmed that bacteria-killing viruses called bacteriophages deploy a sneaky tactic when targeting their hosts: They use a standard genetic code when invading bacteria, then switch to an alternate code at later stages of
![ORNL’s Adam Guss began adapting the SAGE gene editing tool to modify microbes in graduate school. Today, SAGE is rapidly accelerating the design of custom microbes for a variety of applications. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2023-03/GussPetri_2021-P05223_0.png?h=82f92a78&itok=tqHo8Y9C)
A DNA editing tool adapted by Oak Ridge National Laboratory scientists makes engineering microbes for everything from bioenergy production to plastics recycling easier and faster.
![Fungal geneticist Joanna Tannous is gaining a better understanding of the genetic processes behind fungal life to both combat plant disease and encourage beneficial processes like soil carbon storage. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2023-03/2023-P01579.jpg?h=fda684fd&itok=SgSyQYum)
Joanna Tannous has found the perfect organism to study to satisfy her deeply curious nature, her skills in biochemistry and genetics, and a drive to create solutions for a better world. The organism is a poorly understood life form that greatly influences its environment and is unique enough to deserve its own biological kingdom: fungi.
![Oak Ridge National Laboratory’s Dave Weston works in a chamber at the DOE SPRUCE whole ecosystem experiment site in the peatlands of northern Minnesota. Credit: Kyle Pearson/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2023-02/WestonSpruceCropped.jpeg?h=29b91be4&itok=WRDR4xY9)
A quest to understand how Sphagnum mosses facilitate the storage of vast amounts of carbon in peatlands led scientists to a surprising discovery: the plants have sex-based differences that appear to impact the carbon-storing process.
![Computational systems biologists at ORNL worked with the U.S. Department of Veterans Affairs and other institutions to identify 139 locations across the human genome tied to risk factors for varicose veins, marking a first step in the development of new treatments. Credit: Andy Sproles/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2023-01/vein06_0.jpg?h=d32448e0&itok=ItaGWCo5)
As part of a multi-institutional research project, scientists at ORNL leveraged their computational systems biology expertise and the largest, most diverse set of health data to date to explore the genetic basis of varicose veins.
![The Center for Bioenergy Innovation at Oak Ridge National Laboratory has added three new members to its board of directors, from left: Deborah Crawford, vice chancellor for research at the University of Tennessee, Knoxville; Susan Hubbard, deputy for science and technology at ORNL; and Maureen McCann, director of the Biosciences Center at the National Renewable Energy Laboratory. Credit: UT Knoxville, ORNL and NREL.](/sites/default/files/styles/list_page_thumbnail/public/2023-01/cbi_DebSueMaureen01_0.jpg?h=d8871e17&itok=hgZWmY8P)
The Department of Energy’s Center for Bioenergy Innovation, led by Oak Ridge National Laboratory, recently added three new members to its board of directors: Deborah Crawford of the University of Tennessee, Knoxville; Susan Hubbard of ORNL; and Maureen McCann of the National Renewable Energy Laboratory.
![Hybrid poplar trees such as these shown in an ORNL greenhouse were engineered with the REVEILLE1 gene to delay dormancy and produce more biomass. The research was led by the Center for Bioenergy Innovation at ORNL with the Joint Genome Institute, Brookhaven National Laboratory, the HudsonAlpha Institute for Biotechnology, the University of Connecticut and other partners. Credit: Genevieve Martin/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2023-01/PopulusTrees_0.jpg?h=82f92a78&itok=sguDcjBI)
A team of scientists led by ORNL discovered the gene in agave that governs when the plant goes dormant and used it to create poplar trees that nearly doubled in size, increasing biomass yield for biofuels production