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Media Contacts
![The researchers used the new model to accurately identify clusters of gene mutations (spheres), which helped them study the emergence of various genetic diseases. Image credit: Ivaylo Ivanov, Georgia State University.](/sites/default/files/styles/list_page_thumbnail/public/2019-05/med-res-image6_3mb-1.png?h=bf86d530&itok=wTUjuyV_)
Environmental conditions, lifestyle choices, chemical exposure, and foodborne and airborne pathogens are among the external factors that can cause disease. In contrast, internal genetic factors can be responsible for the onset and progression of diseases ranging from degenerative neurological disorders to some cancers.
![U.S. Department of Energy and Cray to Deliver Record-Setting Frontier Supercomputer at ORNL](/sites/default/files/styles/list_page_thumbnail/public/2019-05/Frontier-System-large_0.png?h=bd7af8db&itok=O_aGQSFB)
OAK RIDGE, Tenn., May 7, 2019—The U.S. Department of Energy today announced a contract with Cray Inc. to build the Frontier supercomputer at Oak Ridge National Laboratory, which is anticipated to debut in 2021 as the world’s most powerful computer with a performance of greater than 1.5 exaflops.
![The illustrations show how the correlation between lattice distortion and proton binding energy in a material affects proton conduction in different environments. Mitigating this interaction could help researchers improve the ionic conductivity of solid materials.](/sites/default/files/styles/list_page_thumbnail/public/2019-05/Figure_Rosenthal_5-1-19_0.png?h=73c01546&itok=-tjVhDfm)
Ionic conduction involves the movement of ions from one location to another inside a material. The ions travel through point defects, which are irregularities in the otherwise consistent arrangement of atoms known as the crystal lattice. This sometimes sluggish process can limit the performance and efficiency of fuel cells, batteries, and other energy storage technologies.
![ORNL staff members (from left) Ashley Shields, Michael Galloway, Ketan Maheshwari and Andrew Miskowiec are collaborating on a project focused on predicting and analyzing crystal structures of new uranium oxide phases. Credit: Jason Richards/ORNL](/sites/default/files/styles/list_page_thumbnail/public/2019-03/teamphotoforhighlight_0.jpg?h=a00326b7&itok=O4yDtVj6)
Scientists at the Department of Energy’s Oak Ridge National Laboratory are working to understand both the complex nature of uranium and the various oxide forms it can take during processing steps that might occur throughout the nuclear fuel cycle.
![Molecular dynamics simulations of the Fs-peptide revealed the presence of at least eight distinct intermediate stages during the process of protein folding. The image depicts a fully folded helix (1), various transitional forms (2–8), and one misfolded state (9). By studying these protein folding pathways, scientists hope to identify underlying factors that affect human health.](/sites/default/files/styles/list_page_thumbnail/public/2019-03/Slide1_0.png?h=c855054e&itok=aNbgxXsc)
Using artificial neural networks designed to emulate the inner workings of the human brain, deep-learning algorithms deftly peruse and analyze large quantities of data. Applying this technique to science problems can help unearth historically elusive solutions.
![ORNL researcher Karren More has been elected fellow of the Microscopy Society of America.](/sites/default/files/styles/list_page_thumbnail/public/2019-03/K_More_th.jpg?h=655057a4&itok=53tPHa-r)
OAK RIDGE, Tenn., March 22, 2019 – Karren Leslie More, a researcher at the Department of Energy’s Oak Ridge National Laboratory, has been elected fellow of the Microscopy Society of America (MSA) professional organization.
![(From left) ORNL Associate Laboratory Director for Computing and Computational Sciences Jeff Nichols; ORNL Health Data Sciences Institute Director Gina Tourassi; DOE Deputy Under Secretary for Science Thomas Cubbage; ORNL Task Lead for Biostatistics Blair Christian; and ORNL Research Scientist Ioana Danciu were invited to the White House to showcase an ORNL-developed digital tool aimed at better matching cancer patients with clinical trials.](/sites/default/files/styles/list_page_thumbnail/public/2019-03/TourassiWH%5B1%5D.png?h=26b5064d&itok=HUC2iYmE)
OAK RIDGE, Tenn., March 4, 2019—A team of researchers from the Department of Energy’s Oak Ridge National Laboratory Health Data Sciences Institute have harnessed the power of artificial intelligence to better match cancer patients with clinical trials.
![ORNL alanine_graphic.jpg ORNL alanine_graphic.jpg](/sites/default/files/styles/list_page_thumbnail/public/ORNL%20alanine_graphic.jpg?itok=iRLfcOw-)
OAK RIDGE, Tenn., Jan. 31, 2019—A new electron microscopy technique that detects the subtle changes in the weight of proteins at the nanoscale—while keeping the sample intact—could open a new pathway for deeper, more comprehensive studies of the basic building blocks of life.
![The Consortium for Advanced Simulation of Light Water Reactors uses its Virtual Environment for Reactor Applications (VERA) software for the modeling and simulation of various nuclear reactors, such as the Westinghouse AP1000 pressurized water reactor. The Consortium for Advanced Simulation of Light Water Reactors uses its Virtual Environment for Reactor Applications (VERA) software for the modeling and simulation of various nuclear reactors, such as the Westinghouse AP1000 pressurized water reactor.](/sites/default/files/styles/list_page_thumbnail/public/AP1000_highres_pin_powers.png?itok=5jd5vcFM)
The Department of Energy’s Oak Ridge National Laboratory is collaborating with industry on six new projects focused on advancing commercial nuclear energy technologies that offer potential improvements to current nuclear reactors and move new reactor designs closer to deployment.
![Two neutron diffraction experiments (represented by pink and blue neutron beams) probed a salty solution to reveal its atomic structure. The only difference between the experiments was the identity of the oxygen isotope (O*) that labeled nitrate molecules Two neutron diffraction experiments (represented by pink and blue neutron beams) probed a salty solution to reveal its atomic structure. The only difference between the experiments was the identity of the oxygen isotope (O*) that labeled nitrate molecules](/sites/default/files/styles/list_page_thumbnail/public/news/images/ORNL%202018-G01254-AM-01.jpg?itok=WXkmqIs1)
Scientists at the Department of Energy’s Oak Ridge National Laboratory used neutrons, isotopes and simulations to “see” the atomic structure of a saturated solution and found evidence supporting one of two competing hypotheses about how ions come