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Media Contacts
![ORNL, VA and Harvard researchers developed a sparse matrix full of anonymized information on what is thought to be the largest cohort of healthcare data used for this type of research in the U.S. The matrix can be probed with different methods, such as KESER, to gain new insights into human health. Credit: Nathan Armistead/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2022-04/2022-G00330_KESER%20Illustration_0.jpg?h=1cb48fc4&itok=c6ZuDdDg)
A team of researchers has developed a novel, machine learning–based technique to explore and identify relationships among medical concepts using electronic health record data across multiple healthcare providers.
![Andrew Sutton joined ORNL in 2020 to guide a newly formed team that focuses on chemical process scale-up in advanced manufacturing. Credit: ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2022-04/2022-P01204.jpg?h=8f9cfe54&itok=n2ca9jZz)
When Andrew Sutton arrived at ORNL in late 2020, he knew the move would be significant in more ways than just a change in location.
![An ORNL-led team studied the SARS-CoV-2 spike protein in the trimer state, shown here, to pinpoint structural transitions that could be disrupted to destabilize the protein and negate its harmful effects. Credit: Debsindhu Bhowmik/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2022-01/sars_cov_2_bk.png?h=05c2797f&itok=jQ2D9aTr)
To explore the inner workings of severe acute respiratory syndrome coronavirus 2, or SARS-CoV-2, researchers from ORNL developed a novel technique.
![U.S. Secretary of Energy Granholm tours ORNL’s world-class science facilities](/sites/default/files/styles/list_page_thumbnail/public/2021-11/2021-P09409.jpg?h=036a71b7&itok=C8b0_-Vk)
Energy Secretary Jennifer Granholm visited ORNL on Nov. 22 for a two-hour tour, meeting top scientists and engineers as they highlighted projects and world-leading capabilities that address some of the country’s most complex research and technical challenges.
![Summer Widner, Stephanie Timbs, James Gaugler and James Avenell of ORNL are part of a team that processes thorium-228, a byproduct of actinium-227. As new uses for thorium are realized, particularly in medicine, the lab expects the demand for the radioisotope to grow.](/sites/default/files/styles/list_page_thumbnail/public/2021-08/Part%20of%20Th-228%20Team_1.jpg?h=09b6d1d3&itok=1_l1hx2l)
As a medical isotope, thorium-228 has a lot of potential — and Oak Ridge National Laboratory produces a lot.
![ORNL used novel additive manufacturing techniques to 3D print channel fasteners for Framatome’s boiling water reactor fuel assembly. Four components, like the one shown here, were installed at the TVA Browns Ferry nuclear plant. Credit: Framatome](/sites/default/files/styles/list_page_thumbnail/public/2021-08/3D-printed%20channel%20fastener_0.jpg?h=17d1be53&itok=xLToVHZi)
Four first-of-a-kind 3D-printed fuel assembly brackets, produced at the Department of Energy’s Manufacturing Demonstration Facility at Oak Ridge National Laboratory, have been installed and are now under routine operating
![Researchers studying secondary metabolites in the fungus Aspergillus flavus, pictured, found unique mixes of metabolites corresponding to genetically distinct populations. The finding suggests local environmental conditions play a key role in secondary metabolite production, influencing the discovery of drugs and other useful compounds. Credit: Tomás Allen Rush/ORNL, U.S. Dept. of Energy.](/sites/default/files/styles/list_page_thumbnail/public/2021-07/DSC0351.jpg?h=b2d9f031&itok=PNgYY5eW)
Scientists at ORNL and the University of Wisconsin–Madison have discovered that genetically distinct populations within the same species of fungi can produce unique mixes of secondary metabolites, which are organic compounds with applications in
![An ORNL-led team comprising researchers from multiple DOE national laboratories is using artificial intelligence and computational screening techniques – in combination with experimental validation – to identify and design five promising drug therapy approaches to target the SARS-CoV-2 virus. Credit: Michelle Lehman/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2021-06/frame1.png?h=d1cb525d&itok=51pwBWyP)
An ORNL-led team comprising researchers from multiple DOE national laboratories is using artificial intelligence and computational screening techniques – in combination with experimental validation – to identify and design five promising drug therapy approaches to target the SARS-CoV-2 virus.
![Belinda Akpa applies her diverse expertise and high-performance computing to accelerate the drug discovery process and increase the chances of success when candidate molecules go to clinical trials. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2021-04/2021-P02772_1.jpg?h=0a8b6f8b&itok=seLu5znj)
Belinda Akpa is a chemical engineer with a talent for tackling big challenges and fostering inclusivity and diversity in the next generation of scientists.
![Rich Giannone uses bioanalytical mass spectrometry to examine proteins, the primary driver in biological systems.](/sites/default/files/styles/list_page_thumbnail/public/2021-04/2021-P02194_small.jpg?h=c6980913&itok=bc6MRBX6)
Rich Giannone uses bioanalytical mass spectrometry to examine proteins, the primary driver in biological systems.