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Media Contacts
![Shown here is the structure of the NEMO protein. A team from ORNL conducted extensive molecular dynamics work on Summit by using both quantum mechanics and machine-learning methods to look at the binding affinity of NEMO and 3CLpro in humans and other species and to consider the structural models derived from the sequences of other coronaviruses. Image courtesy Nature Communications, Dan Jacobson/ORNL.](/sites/default/files/styles/list_page_thumbnail/public/2022-09/bradykinin_1.png?h=53873e96&itok=iBwJwFaV)
A new paper published in Nature Communications adds further evidence to the bradykinin storm theory of COVID-19’s viral pathogenesis — a theory that was posited two years ago by a team of researchers at the Department of Energy’s Oak Ridge National Laboratory.
![Data from different sources are joined on platforms created by ORNL researchers to offer better information for decision makers. Credit: ORNL/Nathan Armistead](/sites/default/files/styles/list_page_thumbnail/public/2022-07/COVID%20dashboards%20story%20graphic_0.jpg?h=d1cb525d&itok=ubNOO2W4)
When the COVID-19 pandemic stunned the world in 2020, researchers at ORNL wondered how they could extend their support and help
![Logan Sturm, Alvin M. Weinberg Fellow at ORNL, creates a mashup between additive manufacturing and cybersecurity research. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2022-05/sturm-lab.jpg?h=1de2f7a8&itok=nYiuVTGx)
How an Alvin M. Weinberg Fellow is increasing security for critical infrastructure components
![Andrew Sutton joined ORNL in 2020 to guide a newly formed team that focuses on chemical process scale-up in advanced manufacturing. Credit: ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2022-04/2022-P01204.jpg?h=8f9cfe54&itok=n2ca9jZz)
When Andrew Sutton arrived at ORNL in late 2020, he knew the move would be significant in more ways than just a change in location.
![ORNL research scientist Christa Brelsford explained a mathematical framework she developed in 2018, which showed increased availability of infrastructure didn’t necessarily reduce inequality in its access. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2022-04/image001.jpg?h=1579b22a&itok=XzIna_Uc)
Unequal access to modern infrastructure is a feature of growing cities, according to a study published this week in the Proceedings of the National Academy of Sciences
![An ORNL-led team studied the SARS-CoV-2 spike protein in the trimer state, shown here, to pinpoint structural transitions that could be disrupted to destabilize the protein and negate its harmful effects. Credit: Debsindhu Bhowmik/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2022-01/sars_cov_2_bk.png?h=05c2797f&itok=jQ2D9aTr)
To explore the inner workings of severe acute respiratory syndrome coronavirus 2, or SARS-CoV-2, researchers from ORNL developed a novel technique.
![U.S. Secretary of Energy Granholm tours ORNL’s world-class science facilities](/sites/default/files/styles/list_page_thumbnail/public/2021-11/2021-P09409.jpg?h=036a71b7&itok=C8b0_-Vk)
Energy Secretary Jennifer Granholm visited ORNL on Nov. 22 for a two-hour tour, meeting top scientists and engineers as they highlighted projects and world-leading capabilities that address some of the country’s most complex research and technical challenges.
![ORNL used novel additive manufacturing techniques to 3D print channel fasteners for Framatome’s boiling water reactor fuel assembly. Four components, like the one shown here, were installed at the TVA Browns Ferry nuclear plant. Credit: Framatome](/sites/default/files/styles/list_page_thumbnail/public/2021-08/3D-printed%20channel%20fastener_0.jpg?h=17d1be53&itok=xLToVHZi)
Four first-of-a-kind 3D-printed fuel assembly brackets, produced at the Department of Energy’s Manufacturing Demonstration Facility at Oak Ridge National Laboratory, have been installed and are now under routine operating
![An ORNL-led team comprising researchers from multiple DOE national laboratories is using artificial intelligence and computational screening techniques – in combination with experimental validation – to identify and design five promising drug therapy approaches to target the SARS-CoV-2 virus. Credit: Michelle Lehman/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2021-06/frame1.png?h=d1cb525d&itok=51pwBWyP)
An ORNL-led team comprising researchers from multiple DOE national laboratories is using artificial intelligence and computational screening techniques – in combination with experimental validation – to identify and design five promising drug therapy approaches to target the SARS-CoV-2 virus.
![Parans Paranthaman, a researcher in the Chemical Sciences Division at ORNL, coordinated research efforts to study the filter efficiency of the N95 material. His published results represent one of the first studies on polypropylene as it relates to COVID-19. Credit: ORNL/U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2021-04/2021-P01675.jpg?h=18f5407d&itok=B3UCcJxT)
When COVID-19 was declared a pandemic in March 2020, Oak Ridge National Laboratory’s Parans Paranthaman suddenly found himself working from home like millions of others.