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An ORNL-led team comprising researchers from multiple DOE national laboratories is using artificial intelligence and computational screening techniques – in combination with experimental validation – to identify and design five promising drug therapy approaches to target the SARS-CoV-2 virus. Credit: Michelle Lehman/ORNL, U.S. Dept. of Energy

An ORNL-led team comprising researchers from multiple DOE national laboratories is using artificial intelligence and computational screening techniques – in combination with experimental validation – to identify and design five promising drug therapy approaches to target the SARS-CoV-2 virus.

Vittorio Badalassi, left, of Oak Ridge National Laboratory leads the Fusion Energy Reactor Models Integrator, or FERMI, project, and collaborates with ORNL computational physicist David Green. FERMI applies fission platforms to fusion reactor design. Credit: Commonwealth Fusion Systems and Colby Earles/ORNL, U.S. Dept. of Energy

Oak Ridge National Laboratory expertise in fission and fusion has come together to form a new collaboration, the Fusion Energy Reactor Models Integrator, or FERMI

Nuclear engineer Nesrin Ozgan Cetiner led ORNL’s collaboration with AMS Corp. to test instrument and control sensors for the next generation of nuclear power reactor technology. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

Toward the goal of bringing the next generation of nuclear power reactor technology online this decade, ORNL and Analysis and Measurement Services Corporation have successfully completed loop testing of instrument and control sensors for an advanced reactor design for small modular reactors.

Parans Paranthaman, a researcher in the Chemical Sciences Division at ORNL, coordinated research efforts to study the filter efficiency of the N95 material. His published results represent one of the first studies on polypropylene as it relates to COVID-19. Credit: ORNL/U.S. Dept. of Energy

When COVID-19 was declared a pandemic in March 2020, Oak Ridge National Laboratory’s Parans Paranthaman suddenly found himself working from home like millions of others.

Oscar Martinez loads a special form capsule into the leak tester for a helium leak test in the packaging facility of the National Transportation Research Center. Credit: Jason Richards/ORNL, U.S. Dept. of Energy

As program manager for the Department of Energy’s Oak Ridge National Laboratory’s Package Testing Program, Oscar Martinez enjoys finding and fixing technical issues.

INFUSE logo

The INFUSE fusion program announced a second round of 2020 public-private partnership awards to accelerate fusion energy development.

asset management

East Tennessee occupies a special place in nuclear history. In 1943, the world’s first continuously operating reactor began operating on land that would become ORNL.

Frontier supercomputer

A multi-institutional team, led by a group of investigators at Oak Ridge National Laboratory, has been studying various SARS-CoV-2 protein targets, including the virus’s main protease. The feat has earned the team a finalist nomination for the Association of Computing Machinery, or ACM, Gordon Bell Special Prize for High Performance Computing-Based COVID-19 Research.

Chuck Kessel

Chuck Kessel was still in high school when he saw a scientist hold up a tiny vial of water and say, “This could fuel a house for a whole year.”

coronavirus

NellOne Therapeutics has licensed a drug delivery system from the Department of Energy’s Oak Ridge National Laboratory that is designed to transport therapeutics directly to cells infected by SARS-CoV-2, the virus causing COVID-19.