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![ORNL, VA and Harvard researchers developed a sparse matrix full of anonymized information on what is thought to be the largest cohort of healthcare data used for this type of research in the U.S. The matrix can be probed with different methods, such as KESER, to gain new insights into human health. Credit: Nathan Armistead/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2022-04/2022-G00330_KESER%20Illustration_0.jpg?h=1cb48fc4&itok=c6ZuDdDg)
A team of researchers has developed a novel, machine learning–based technique to explore and identify relationships among medical concepts using electronic health record data across multiple healthcare providers.
![An ORNL-led team studied the SARS-CoV-2 spike protein in the trimer state, shown here, to pinpoint structural transitions that could be disrupted to destabilize the protein and negate its harmful effects. Credit: Debsindhu Bhowmik/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2022-01/sars_cov_2_bk.png?h=05c2797f&itok=jQ2D9aTr)
To explore the inner workings of severe acute respiratory syndrome coronavirus 2, or SARS-CoV-2, researchers from ORNL developed a novel technique.
![This protein drives key processes for sulfide use in many microorganisms that produce methane, including Thermosipho melanesiensis. Researchers used supercomputing and deep learning tools to predict its structure, which has eluded experimental methods such as crystallography. Credit: Ada Sedova/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2022-01/thermosipho_collabfold2_0.jpg?h=3432ff3c&itok=4xhLbjKZ)
A team of scientists led by the Department of Energy’s Oak Ridge National Laboratory and the Georgia Institute of Technology is using supercomputing and revolutionary deep learning tools to predict the structures and roles of thousands of proteins with unknown functions.
![Erdem Asa is leveraging his power electronics expertise to adapt ORNL’s wireless charging technology to unmanned aerial vehicles. Credit: Erdem Asa/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2021-11/ErdemAsa_desk_0.jpg?h=2acae37d&itok=upTbxI6G)
Having co-developed the power electronics behind ORNL’s compact, high-level wireless power technology for automobiles, Erdem Asa is looking to the skies to apply the same breakthrough to aviation.
![Hope Corsair. Credit: Carlos Jones, ORNL/U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2021-09/2021-P06397.jpg?h=2e75806b&itok=T_4C_X35)
When Hope Corsair’s new colleagues at Oak Ridge National Laboratory ask her about her area of expertise, she tells them it’s “context.” Her goal as an energy economist is to make sure ORNL’s breakthroughs have the widest possible
![ORNL used novel additive manufacturing techniques to 3D print channel fasteners for Framatome’s boiling water reactor fuel assembly. Four components, like the one shown here, were installed at the TVA Browns Ferry nuclear plant. Credit: Framatome](/sites/default/files/styles/list_page_thumbnail/public/2021-08/3D-printed%20channel%20fastener_0.jpg?h=17d1be53&itok=xLToVHZi)
Four first-of-a-kind 3D-printed fuel assembly brackets, produced at the Department of Energy’s Manufacturing Demonstration Facility at Oak Ridge National Laboratory, have been installed and are now under routine operating
![An ORNL-led team comprising researchers from multiple DOE national laboratories is using artificial intelligence and computational screening techniques – in combination with experimental validation – to identify and design five promising drug therapy approaches to target the SARS-CoV-2 virus. Credit: Michelle Lehman/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2021-06/frame1.png?h=d1cb525d&itok=51pwBWyP)
An ORNL-led team comprising researchers from multiple DOE national laboratories is using artificial intelligence and computational screening techniques – in combination with experimental validation – to identify and design five promising drug therapy approaches to target the SARS-CoV-2 virus.
![Kashif Nawaz, researcher and group leader for multifunctional equipment integration in buildings technologies, is developing a platform for the direct air capture of carbon dioxide that can be retrofitted to existing rooftop heating, ventilation and air conditioning units. Credit: ORNL/U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2021-03/2021-P01088_small.jpg?h=036a71b7&itok=iOYUTtfS)
When Kashif Nawaz looks at a satellite map of the U.S., he sees millions of buildings that could hold a potential solution for the capture of carbon dioxide, a plentiful gas that can be harmful when excessive amounts are released into the atmosphere, raising the Earth’s temperature.
![The researchers embedded a programmable model into a D-Wave quantum computer chip. Credit: D-Wave](/sites/default/files/styles/list_page_thumbnail/public/2021-02/P5-o5czF_0.jpg?h=b69e0e0e&itok=wCU6WIp_)
Since the 1930s, scientists have been using particle accelerators to gain insights into the structure of matter and the laws of physics that govern our world.
![ORNL researchers in advanced manufacturing, materials science and engineering collaborated to produce face shields and reusable mask molds so that industry can quickly mass produce. Credit: Carlos Jones/Oak Ridge National Laboratory, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2020-05/MDF_group_shot.jpg?h=5e9da067&itok=hx6y5O6o)
The University of Texas at San Antonio (UTSA) has formally launched the Cybersecurity Manufacturing Innovation Institute (CyManII), a $111 million public-private partnership.