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Media Contacts
![An ORNL-led team studied the SARS-CoV-2 spike protein in the trimer state, shown here, to pinpoint structural transitions that could be disrupted to destabilize the protein and negate its harmful effects. Credit: Debsindhu Bhowmik/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2022-01/sars_cov_2_bk.png?h=05c2797f&itok=jQ2D9aTr)
To explore the inner workings of severe acute respiratory syndrome coronavirus 2, or SARS-CoV-2, researchers from ORNL developed a novel technique.
![This protein drives key processes for sulfide use in many microorganisms that produce methane, including Thermosipho melanesiensis. Researchers used supercomputing and deep learning tools to predict its structure, which has eluded experimental methods such as crystallography. Credit: Ada Sedova/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2022-01/thermosipho_collabfold2_0.jpg?h=3432ff3c&itok=4xhLbjKZ)
A team of scientists led by the Department of Energy’s Oak Ridge National Laboratory and the Georgia Institute of Technology is using supercomputing and revolutionary deep learning tools to predict the structures and roles of thousands of proteins with unknown functions.
![Ten scientists from the Department of Energy’s Oak Ridge National Laboratory are among the world’s most highly cited researchers. Credit: ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2021-11/2008-P01679_0.jpg?h=6acbff97&itok=ewBiiftq)
Ten scientists from the Department of Energy’s Oak Ridge National Laboratory are among the world’s most highly cited researchers, according to a bibliometric analysis conducted by the scientific publication analytics firm Clarivate.
![Researchers gained new insights into the mechanisms some methane-feeding bacteria called methanotrophs (pictured) use to break down the toxin methylmercury. Credit: Andy Sproles/ORNL, U.S. Dept. of Energy; Jeremy Semrau/Univ. of Michigan](/sites/default/files/styles/list_page_thumbnail/public/2021-09/OB3b_5Cu_5a01.jpg?h=535a555c&itok=FLOo_uRv)
A team led by ORNL and the University of Michigan have discovered that certain bacteria can steal an essential compound from other microbes to break down methane and toxic methylmercury in the environment.
![A traffic-camera view of Shallowford Road, one of the more than 350 intersections in Chattanooga studied by Oak Ridge National Laboratory researchers.](/sites/default/files/styles/list_page_thumbnail/public/2021-09/ChattMobilityMain.png?h=29234840&itok=a5Mj37qW)
The daily traffic congestion along the streets and interstate lanes of Chattanooga could be headed the way of the horse and buggy with help from ORNL researchers.
![The Oak Ridge National Environmental Research Park encompasses a 20,000 acre area that includes Oak Ridge National Laboratory. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2021-09/2019-P16158_0.jpg?h=036a71b7&itok=_6tQ24p4)
Anyone familiar with ORNL knows it’s a hub for world-class science. The nearly 33,000-acre space surrounding the lab is less known, but also unique.
![As the leader of ORNL’s Biodiversity and Ecosystem Health Group, environmental scientist Teresa Mathews works to understand the impacts of energy generation on water and solve challenging problems, including mercury pollution. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2021-08/2021-P05311%5B10%5D%5B13%5D_0.jpg?h=f99713cc&itok=zd0wGqpx)
Moving to landlocked Tennessee isn’t an obvious choice for most scientists with new doctorate degrees in coastal oceanography.
![Researchers studying secondary metabolites in the fungus Aspergillus flavus, pictured, found unique mixes of metabolites corresponding to genetically distinct populations. The finding suggests local environmental conditions play a key role in secondary metabolite production, influencing the discovery of drugs and other useful compounds. Credit: Tomás Allen Rush/ORNL, U.S. Dept. of Energy.](/sites/default/files/styles/list_page_thumbnail/public/2021-07/DSC0351.jpg?h=b2d9f031&itok=PNgYY5eW)
Scientists at ORNL and the University of Wisconsin–Madison have discovered that genetically distinct populations within the same species of fungi can produce unique mixes of secondary metabolites, which are organic compounds with applications in
![An ORNL-led team comprising researchers from multiple DOE national laboratories is using artificial intelligence and computational screening techniques – in combination with experimental validation – to identify and design five promising drug therapy approaches to target the SARS-CoV-2 virus. Credit: Michelle Lehman/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2021-06/frame1.png?h=d1cb525d&itok=51pwBWyP)
An ORNL-led team comprising researchers from multiple DOE national laboratories is using artificial intelligence and computational screening techniques – in combination with experimental validation – to identify and design five promising drug therapy approaches to target the SARS-CoV-2 virus.
![ORNL’s Sergei Kalinin and Rama Vasudevan (foreground) use scanning probe microscopy to study bulk ferroelectricity and surface electrochemistry -- and generate a lot of data. Credit: Jason Richards/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2021-05/KalininVasudevan_2017-P03014_0.jpg?h=1116cd87&itok=KEEOB4hi)
At the Department of Energy’s Oak Ridge National Laboratory, scientists use artificial intelligence, or AI, to accelerate the discovery and development of materials for energy and information technologies.