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Media Contacts
![Researchers studying secondary metabolites in the fungus Aspergillus flavus, pictured, found unique mixes of metabolites corresponding to genetically distinct populations. The finding suggests local environmental conditions play a key role in secondary metabolite production, influencing the discovery of drugs and other useful compounds. Credit: Tomás Allen Rush/ORNL, U.S. Dept. of Energy.](/sites/default/files/styles/list_page_thumbnail/public/2021-07/DSC0351.jpg?h=b2d9f031&itok=PNgYY5eW)
Scientists at ORNL and the University of Wisconsin–Madison have discovered that genetically distinct populations within the same species of fungi can produce unique mixes of secondary metabolites, which are organic compounds with applications in
![ORNL’s Josh Michener, a microbiologist and metabolic engineer, led the discovery of a useful new enzyme that breaks down stubborn bonds in lignin, a polymer found in plants that typically becomes waste during bioconversion. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2021-06/2019-P05683_0.jpg?h=4c5cadcc&itok=FSVdbEYP)
In a step toward increasing the cost-effectiveness of renewable biofuels and bioproducts, scientists at ORNL discovered a microbial enzyme that degrades tough-to-break bonds in lignin, a waste product of biorefineries.
![Brian Davison portrait](/sites/default/files/styles/list_page_thumbnail/public/2022-06/2018-P07469_thumbnail.jpg?h=8f9cfe54&itok=jhC_89-r)
In a long career full of scientific accomplishments, Brian Davison counts among his many successes the formation of ORNL’s LGBTQIA+ employee group and helping gay and lesbian staff at the lab
![An ORNL-led team comprising researchers from multiple DOE national laboratories is using artificial intelligence and computational screening techniques – in combination with experimental validation – to identify and design five promising drug therapy approaches to target the SARS-CoV-2 virus. Credit: Michelle Lehman/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2021-06/frame1.png?h=d1cb525d&itok=51pwBWyP)
An ORNL-led team comprising researchers from multiple DOE national laboratories is using artificial intelligence and computational screening techniques – in combination with experimental validation – to identify and design five promising drug therapy approaches to target the SARS-CoV-2 virus.
![A research team led by ORNL’s Xiaohan Yang used a gene from agave to engineer higher yield, improved stress tolerance and greater carbon sequestration in tobacco plants. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2021-06/2019-P09831.jpg?h=39b94f55&itok=8O8d7xMb)
Scientists at ORNL have discovered a single gene that simultaneously boosts plant growth and tolerance for stresses such as drought and salt, all while tackling the root cause of climate change by enabling plants to pull more carbon dioxide from the atmosphere.
![ORNL’s Sergei Kalinin and Rama Vasudevan (foreground) use scanning probe microscopy to study bulk ferroelectricity and surface electrochemistry -- and generate a lot of data. Credit: Jason Richards/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2021-05/KalininVasudevan_2017-P03014_0.jpg?h=1116cd87&itok=KEEOB4hi)
At the Department of Energy’s Oak Ridge National Laboratory, scientists use artificial intelligence, or AI, to accelerate the discovery and development of materials for energy and information technologies.
![Belinda Akpa applies her diverse expertise and high-performance computing to accelerate the drug discovery process and increase the chances of success when candidate molecules go to clinical trials. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2021-04/2021-P02772_1.jpg?h=0a8b6f8b&itok=seLu5znj)
Belinda Akpa is a chemical engineer with a talent for tackling big challenges and fostering inclusivity and diversity in the next generation of scientists.
![ORNL ecosystem scientist Colleen Iversen talked to fourth-grade students at Coulter Grove Intermediate School in Maryville on Friday, April 23, as part of National Environmental Education Week.](/sites/default/files/styles/list_page_thumbnail/public/2021-04/Sciencetalk3_1.jpg?h=29234840&itok=wWaAJG05)
Esther Parish is one of eight scientists from the Department of Energy's Oak Ridge National Laboratory talking to students in nine schools across East Tennessee as part of National Environmental Education Week, or EE Week.
![Rich Giannone uses bioanalytical mass spectrometry to examine proteins, the primary driver in biological systems.](/sites/default/files/styles/list_page_thumbnail/public/2021-04/2021-P02194_small.jpg?h=c6980913&itok=bc6MRBX6)
Rich Giannone uses bioanalytical mass spectrometry to examine proteins, the primary driver in biological systems.
![ATOM logo](/sites/default/files/styles/list_page_thumbnail/public/2021-03/ATOM_Logo_small.png?h=8f9cfe54&itok=Qpezfk8V)
The Accelerating Therapeutics for Opportunities in Medicine , or ATOM, consortium today announced the U.S. Department of Energy’s Oak Ridge, Argonne and Brookhaven national laboratories are joining the consortium to further develop ATOM’s artificial intelligence, or AI-driven, drug discovery platform.