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Representatives from The University of Toledo and the U.S. Department of Energy’s Oak Ridge National Laboratory (ORNL) in Tennessee are teaming up to conduct collaborative automotive materials research.” Credit: University of Toledo

ORNL, University of Toledo to collaborate on advanced materials, manufacturing research for vehicle applications

ORNL and The University of Toledo have entered into a memorandum of understanding for collaborative research.

As part of DOE’s HPC4Mobility initiative ORNL researchers developed machine learning algorithms that can control smart traffic lights at intersections to facilitate the smooth flow of traffic and increase fuel efficiency.

ORNL research supports an efficient, clean, secure transportation future

A modern, healthy transportation system is vital to the nation’s economic security and the American standard of living. The U.S. Department of Energy’s Oak Ridge National Laboratory (ORNL) is engaged in a broad portfolio of scientific research for improved mobility

Tyler Gerczak, a materials scientist at Oak Ridge National Laboratory, is focused on post-irradiation examination and separate effects testing of current fuels for light water reactors and advanced fuel types that could be used in future nuclear systems. Credit: Carlos Jones/Oak Ridge National Laboratory, U.S. Dept. of Energy

Tyler Gerczak: ‘Moonlighting’ for nuclear fuels

Ask Tyler Gerczak to find a negative in working at the Department of Energy’s Oak Ridge National Laboratory, and his only complaint is the summer weather. It is not as forgiving as the summers in Pulaski, Wisconsin, his hometown.

Project bridges compute staff, resources at ORNL and VA health data to speed suicide risk screening for US veterans. Image Credit: Carlos Jones, ORNL

ORNL-VA collaboration targets veteran suicide epidemic

More than 6,000 veterans died by suicide in 2016, and from 2005 to 2016, the rate of veteran suicides in the United States increased by more than 25 percent.

Hong Wang, a senior distinguished researcher at the National Transportation Research Center, uses applied mathematics and modeling to improve transportation systems.

Predicting the unpredictable: Hong Wang applies novel theory to smooth traffic flow

In Hong Wang’s world, nothing is beyond control. Before joining Oak Ridge National Laboratory as a senior distinguished researcher in transportation systems, he spent more than three decades studying the control of complex industrial systems in the United Kingdom. 

Veda Galigekere is leading Oak Ridge National Laboratory’s work on fast, efficient, wireless charging of electric vehicles.

Veda Galigekere: The integrated, electric mobility future

Galigekere is principal investigator for the breakthrough work in fast, wireless charging of electric vehicles being performed at the National Transportation Research Center at Oak Ridge National Laboratory.

U.S. Department of Energy and Cray to Deliver Record-Setting Frontier Supercomputer at ORNL

U.S. Department of Energy and Cray to Deliver Record-Setting Frontier Supercomputer at ORNL

OAK RIDGE, Tenn., May 7, 2019—The U.S. Department of Energy today announced a contract with Cray Inc. to build the Frontier supercomputer at Oak Ridge National Laboratory, which is anticipated to debut in 2021 as the world’s most powerful computer with a performance of greater than 1.5 exaflops.

Molecular dynamics simulations of the Fs-peptide revealed the presence of at least eight distinct intermediate stages during the process of protein folding. The image depicts a fully folded helix (1), various transitional forms (2–8), and one misfolded state (9). By studying these protein folding pathways, scientists hope to identify underlying factors that affect human health.

Modified deep-learning algorithms unveil features of shape-shifting proteins

Using artificial neural networks designed to emulate the inner workings of the human brain, deep-learning algorithms deftly peruse and analyze large quantities of data. Applying this technique to science problems can help unearth historically elusive solutions.

Illustration of the intricate organization of the PKA structure, wherein different parts of the protein are connected through elaborate hydrogen bonding networks (dashed yellow lines), glued together by the hydrophobic assemblies (light blue and orange volumes)—all working together to build the functional active site. Insert shows protonation of the transferred phosphoryl group (cyan mesh) and its many interactions with water and the active site amino acid residues. Credit: Jill Hemman/ORNL

Neutrons paint atomic portrait of prototypical cell signaling enzyme

OAK RIDGE, Tenn., March 20, 2019—Direct observations of the structure and catalytic mechanism of a prototypical kinase enzyme—protein kinase A or PKA—will provide researchers and drug developers with significantly enhanced abilities to understand and treat fatal diseases and neurological disorders such as cancer, diabetes, and cystic fibrosis.

(From left) ORNL Associate Laboratory Director for Computing and Computational Sciences Jeff Nichols; ORNL Health Data Sciences Institute Director Gina Tourassi; DOE Deputy Under Secretary for Science Thomas Cubbage; ORNL Task Lead for Biostatistics Blair Christian; and ORNL Research Scientist Ioana Danciu were invited to the White House to showcase an ORNL-developed digital tool aimed at better matching cancer patients with clinical trials.

New ORNL AI tool revolutionizes process for matching cancer patients with clinical trials

OAK RIDGE, Tenn., March 4, 2019—A team of researchers from the Department of Energy’s Oak Ridge National Laboratory Health Data Sciences Institute have harnessed the power of artificial intelligence to better match cancer patients with clinical trials.